Evidence map›Paper›PMID 39903686›Full record

SynthesisPloS one2025

Effect of power training on physical functional performance of patients with Parkinson's disease: A systematic review and meta-analysis of randomized controlled trials.

Samuel Brito de Almeida, Emmanuelle Silva Tavares Sobreira, Charles Phillipe de Lucena Alves, Danielle Pessoa Lima, Janine de Carvalho Bonfadini, Manoel Alves Sobreira-Neto, Thiago Holanda Freitas, Simony Lira do Nascimento, Pedro Braga-Neto

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samuel Brito de AlmeidaClinical Research Unit, Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, Ceara, Brazil.ORCID 0000-0001-6174-1839
Emmanuelle Silva Tavares SobreiraClinical Research Unit, Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, Ceara, Brazil.
Charles Phillipe de Lucena AlvesGraduate Program in Epidemiology, University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Danielle Pessoa LimaClinical Research Unit, Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, Ceara, Brazil.ORCID 0000-0003-4591-727X
Janine de Carvalho BonfadiniClinical Research Unit, Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, Ceara, Brazil.
Manoel Alves Sobreira-NetoDivision of Neurology, Federal University of Ceará, Fortaleza, Ceara, Brazil.
Thiago Holanda FreitasDepartment of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.
Simony Lira do NascimentoDepartment of Physical Therapy, Federal University of Ceara, Fortaleza, Ceará, Brazil.ORCID 0000-0001-6248-5590
Pedro Braga-NetoDivision of Neurology, Federal University of Ceará, Fortaleza, Ceara, Brazil.ORCID 0000-0001-9186-9243

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionParkinson's disease (PD) is becoming more prevalent, highlighting the urgency of developing treatments to minimize its effects on muscular strength and physical function. Power training (PT) is a potential approach that may improve endurance and muscular power, essential for maintaining functional ability in PD.

objectiveTo compare the effect of PT versus control or other physical activity (PA) interventions on physical functional performance (PFP) in PD patients.

methodsWe searched PubMed, MEDLINE, Embase, LILACS, PEDro, Cochrane Library, and Scopus. Inclusion criteria were randomized controlled trials comparing PT to a control group or another PA intervention in PD patients. PFP was the primary outcome. Pooled effect estimates were calculated from baseline to endpoint scores.

resultsFrom 21,558 results, four studies were included in the meta-analysis due to their moderate to high methodological quality. PT showed no significant effect on PFP outcomes compared to control groups (TUG: ES, -0.281; 95% CI, -0.693 to 0.130; P = 0.180; I2:0%; PWS: ES, 0.748; 95% CI, -0.768 to 2.265; P = 0.333; I2:88%; FWS: ES, 0.420; 95% CI, -0.950 to 1.791; P = 0.548; I2:83%; SLS: ES, 0.161; 95% CI, -0.332 to 0.655; P = 0.521; I2:0%). No differences were found between PT and alternative interventions (TUG: ES, 0.132; 95% CI, -0.394 to 0.657; P = 0.623; I2:0%; BBA: ES, 0.057; 95% CI, -0.430 to 0.544; P = 0.820; I2:0%).

conclusionPT did not improve PFP compared to control or alternative interventions. More studies are needed to explore PT effects (e.g., higher volume, intensity, and combined types) in PD patients.

Indexed as

Parkinson DiseasePhysical Functional PerformanceResistance TrainingExerciseHumansMuscle StrengthRandomized Controlled Trials as Topic

Identifiers

PMID39903686
PMCPMC11793793

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.