Evidence map›Paper›PMID 39903523›Full record

SynthesisInternational journal of surgery (London, England)2025

Iatrogenic nerve injury following pelvic ring injury: a network meta-analysis.

Yu-Cheng Su, Yung-Heng Hsu, Ying-Chao Chou, I-Jung Chen, Chih-Yang Lai, Yi-Hsun Yu

Abstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in International journal of surgery (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yu-Cheng SuLinkou Chang Gung Memorial Hospital, Taoyuan City, Taiwan.
Yung-Heng HsuDepartment of Orthopedic Surgery, Musculoskeletal Research Center, Chang Gung Memorial Hospital and Chang Gung University, Tao-Yuan, Taiwan.
Ying-Chao ChouDepartment of Orthopedic Surgery, Musculoskeletal Research Center, Chang Gung Memorial Hospital and Chang Gung University, Tao-Yuan, Taiwan.
I-Jung ChenDepartment of Orthopedic Surgery, Musculoskeletal Research Center, Chang Gung Memorial Hospital and Chang Gung University, Tao-Yuan, Taiwan.
Chih-Yang LaiDepartment of Orthopedic Surgery, Musculoskeletal Research Center, Chang Gung Memorial Hospital and Chang Gung University, Tao-Yuan, Taiwan.
Yi-Hsun YuDepartment of Orthopedic Surgery, Musculoskeletal Research Center, Chang Gung Memorial Hospital and Chang Gung University, Tao-Yuan, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPelvic ring injuries are common in multi-trauma patients and can be life-threatening, necessitating prompt surgical intervention to improve outcomes. However, surgery can lead to complications such as iatrogenic nerve injury. This network meta-analysis aimed to improve outcomes in multi-trauma patients with pelvic ring injuries by evaluating the incidence of iatrogenic nerve injuries, identifying vulnerable nerves, and comparing different fixation methods. MATERIALS AND

methodsA systematic search of MEDLINE, EMBASE, and Scopus from inception to 5 December 2023 revealed 29 comparative studies on the incidence of iatrogenic nerve injury in 1561 adult patients with pelvic ring injuries. Data were extracted on study and patient characteristics, iatrogenic nerve injury incidences, and specific nerve injuries. A random-effects model assessed treatment effects, with subgroup analysis and meta-regression. The main outcomes included odds ratios (ORs) and confidence intervals (CIs) for iatrogenic nerve injuries.

resultsCompared with closed reduction internal fixation, robotic-assisted techniques had the highest, and open reduction internal fixation had the lowest ORs for iatrogenic nerve injuries. The robotic-assisted approach ranked best with an OR of 0.22 (95% CI: 0.02-2.16), while closed reduction internal fixation with the anterior approach (OR: 0.71; 95% CI: 0.21-2.48) and open reduction internal fixation with the anterior approach performed the worst. The lateral femoral cutaneous nerve was injured in all open reduction internal fixation with anterior approach procedures and in 66.7% of open reduction internal fixation with posterior approach procedures. Meta-regression showed a significantly lower OR for iatrogenic nerve injuries in patients aged >41.4 years in the open reduction internal fixation with the anterior approach group (OR: 0.02; 95% CI: 0.001-0.63; P  = 0.026) compared with younger patients.

conclusionThe robotic-assisted technique may result in the fewest iatrogenic nerve injuries during the treatment of pelvic ring injuries. The posterior approach may also reduce the risk of iatrogenic nerve injuries.

Indexed as

Fracture Fixation, InternalFractures, BoneIatrogenic DiseasePelvic BonesPeripheral Nerve InjuriesHumansPostoperative ComplicationsRobotic Surgical Procedures

Identifiers

PMID39903523
PMCPMC12372741

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.