Evidence map›Paper›PMID 39903388›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2025

In Vitro Study of the Biological Activity of Aloe barbadensis Miller and its Physicochemical Characterization.

Arturo Alberto Velázquez-López, Margarita Torres-Gregorio, Vanessa García-Rojas, Humberto Hernández-Sánchez, Rosalva Mora-Escobedo

Abstract read
PubMed Publisher
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Arturo Alberto Velázquez-LópezInstituto Politécnico Nacional, ENCB, Campus Zacatenco. Miguel Othón de Mendizábal 699, Alcaldía G.A. Madero, Ciudad de México, CDMX, México, C.P. 07360, México. arturo.velazquez2302@gmail.com.ORCID http://orcid.org/0000-0002-7366-9130
Margarita Torres-GregorioInstituto Politécnico Nacional, ENCB, Campus Zacatenco. Miguel Othón de Mendizábal 699, Alcaldía G.A. Madero, Ciudad de México, CDMX, México, C.P. 07360, México.
Vanessa García-RojasInstituto Politécnico Nacional, ENCB, Campus Zacatenco. Miguel Othón de Mendizábal 699, Alcaldía G.A. Madero, Ciudad de México, CDMX, México, C.P. 07360, México.ORCID http://orcid.org/0000-0002-9634-3598
Humberto Hernández-SánchezInstituto Politécnico Nacional, ENCB, Campus Zacatenco. Miguel Othón de Mendizábal 699, Alcaldía G.A. Madero, Ciudad de México, CDMX, México, C.P. 07360, México.ORCID http://orcid.org/0000-0003-0769-8037
Rosalva Mora-EscobedoInstituto Politécnico Nacional, ENCB, Campus Zacatenco. Miguel Othón de Mendizábal 699, Alcaldía G.A. Madero, Ciudad de México, CDMX, México, C.P. 07360, México. rosalmorae@gmail.com.ORCID http://orcid.org/0000-0003-3197-1187

Funding

Consejo Nacional de Humanidades, Ciencias y Tecnologías CBF2023-2024-4902SIP: Proyecto Multidisciplinario 20240488
6 · The paper itself

Abstract

Aloe barbadensis is a natural source of bioactive compounds whose combined effects have been linked to the improvement of several diseases. There is scientific evidence obtained through in vitro and in vivo assays showing the possible benefits of aloe gel. The aim of this research was to characterize and determine the in vitro antioxidant, anti-inflammatory, antihypertensive and antibacterial capacities of aloe gel extract. The gel was extracted by removing the exocarp of aloe leaves. Physicochemical characterization, antioxidant activity, quantification of phenolic compounds, spectroscopic techniques (Fourier Transform Infrared (FTIR), Raman, XPS and XRD) and in vitro biological activities were then performed. The aloe gel contained 66.95% of polysaccharides, corresponding to dietary fiber. FTIR and Raman spectroscopy revealed bands of functional groups (e.g., COO-, CO-, and OH) related to the structure of polymannans. X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD) analyses revealed the presence of minerals such as manganese, magnesium, molybdenum, potassium, sodium, and cobalt. The phenolic compounds identified by HPLC were diverse, highlighting the presence of aloe emodin, aloin and gallic acid. The aloe gel exhibited anti-inflammatory, antihypertensive and antibacterial (Salmonella Typhi, Escherichia coli and Staphylococcus aureus) activities, indicating the possible use of Aloe barbadensis M. as a therapeutic agent for the treatment of diseases.

Indexed as

AloeAnti-Bacterial AgentsAntioxidantsPlant ExtractsAnthraquinonesAntihypertensive AgentsAnti-Inflammatory AgentsDietary FiberEmodinEscherichia coliGallic AcidPhenolsPlant LeavesPolysaccharidesSpectroscopy, Fourier Transform InfraredX-Ray Diffractionalloinaloe emodinAnthraquinonesAnti-Bacterial AgentsAntihypertensive AgentsAnti-Inflammatory AgentsAntioxidantsDietary FiberEmodinGallic AcidPhenolsPlant ExtractsPolysaccharidesAloe barbadensis M.Biological activityPhysicochemical characterizationPolyphenols

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.