Evidence map›Paper›PMID 39903315›Full record

ArticleCurrent microbiology2025

Phenotypic and Molecular Characterization of Extended-Spectrum β-Lactamase, Plasmid-Mediated- AmpC, and Carbapenemase-Producing Enterobacteriaceae Isolated from Companion and Production Animals in Brazil.

Larissa M Chicoski, Arthur R da Costa, Maísa F Menck-Costa, Francisco E Pereira Rocha, Raffaella M Mainardi, Alais M Dall Agnol, Ulisses P Pereira

Abstract read
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In one paragraph

Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Larissa M ChicoskiPost Graduate Program of Animal Science, Department of Preventive Veterinary Medicine, Universidade Estadual de Londrina, Celso Garcia Cid Road, PR455 Km 380, PO Box 10011, Londrina, Paraná, 86057-970, Brazil.ORCID http://orcid.org/0000-0002-9909-0100
Arthur R da CostaLaboratory of Animal Bacteriology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Celso Garcia Cid Road, PR455 Km 380, PO Box 10011, Londrina, Paraná, 86057-970, Brazil.ORCID http://orcid.org/0000-0002-8943-4715
Maísa F Menck-CostaLaboratory of Basic and Applied Bacteriology, Department of Microbiology, Universidade Estadual de Londrina, Celso Garcia Cid Road, PR455 Km 380, PO Box 10011, Londrina, Paraná, 86057-970, Brazil.ORCID http://orcid.org/0000-0002-6788-7182
Francisco E Pereira RochaPost Graduate Program of Animal Science, Department of Preventive Veterinary Medicine, Universidade Estadual de Londrina, Celso Garcia Cid Road, PR455 Km 380, PO Box 10011, Londrina, Paraná, 86057-970, Brazil.ORCID http://orcid.org/0000-0002-7944-1030
Raffaella M MainardiLaboratory of Animal Bacteriology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Celso Garcia Cid Road, PR455 Km 380, PO Box 10011, Londrina, Paraná, 86057-970, Brazil.ORCID http://orcid.org/0000-0003-0569-960X
Alais M Dall AgnolLaboratory of Animal Bacteriology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Celso Garcia Cid Road, PR455 Km 380, PO Box 10011, Londrina, Paraná, 86057-970, Brazil.ORCID http://orcid.org/0000-0002-0420-820X
Ulisses P PereiraLaboratory of Animal Bacteriology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Celso Garcia Cid Road, PR455 Km 380, PO Box 10011, Londrina, Paraná, 86057-970, Brazil. upaduapereira@uel.br.ORCID http://orcid.org/0000-0003-4868-4459

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 408898/2022-4
6 · The paper itself

Abstract

The crisis of bacterial resistance is an emerging One Health challenge, driven by the overuse of antimicrobials in medical and agricultural settings. This study aimed to investigate extended-spectrum β-lactamase (ESBL), Ampicillinase (AmpC), and carbapenemase production, and the presence of genes encoding these enzymes in Escherichia coli, Klebsiella spp., and Proteus spp., major contributors to infections and resistance isolates from animals. From 2016 to 2021, 130 multidrug-resistant (MDR) or extensively drug-resistant (XDR) isolates were recovered from the secretions, excretions, and organs of companion and production animals with active infections. Antibacterial sensitivity tests, along with phenotypic and genotypic detection of resistance enzymes, were performed. To the best of our knowledge, this is the first study in Brazil to estimate the prevalence of XDR Enterobacteriales isolated from companion and production animals, which accounted for 13.8% of the strains. Statistically significant differences (P < 0.05) in resistant bacteria between different classes and within the same class of antibacterial bacteria were found. The statistical probability between genotypic detection of ESBL (OR = 3.1) and phenotypic tests for AmpC (OR = 2.3) was also established. Approximately 32.3%, 17.6%, and 16.8% of the strains had positive phenotypic tests for ESBL, AmpC, and carbapenemases, respectively. Genetic analysis revealed the presence of bla

Indexed as

Bacterial Proteinsbeta-LactamasesEnterobacteriaceaeEnterobacteriaceae InfectionsPetsAnimalsAnti-Bacterial AgentsBrazilDrug Resistance, Multiple, BacterialMicrobial Sensitivity TestsPhenotypePlasmidsAmpC beta-lactamasesAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamasescarbapenemase

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.