ArticleCurrent microbiology2025
Evaluation of Antibiotic-Sensitive Bacillus Strain as a Potential Probiotic for Enhanced Growth in Penaeus vannamei.
Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Exploring the Microbial Flora Associated with Penaeidae Shrimp Habitats Along the Northeastern Mediterranean Coast of Egypt.Current microbiology · 2026Article
- Screening of Antibiotic-Sensitive Lactic Acid Bacteria (LAB) Associated with the Gut of Penaeus Vannamei and its Application in Shrimp Farming.Current microbiology · 2025Article
- Host genome drives the microbiota enrichment of beneficial microbes in shrimp: exploring the hologenome perspective.Animal microbiome · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The safety of probiotics in aquaculture, particularly concerning the transfer of antibiotic resistance genes (ARGs), has become a significant concern. This study aims to isolate antibiotic-sensitive Bacillus strains from the gut of Penaeus vannamei and evaluate the potential for practical application in shrimp farming. The strain was tested for antibiotic sensitivity to 10 commonly used antibiotics, and the minimum inhibitory concentration (MIC) values were determined. Morphological analysis and 16S rRNA sequencing confirmed its identity. The probiotic properties, antibacterial activity, and feeding effects on P. vannamei were also assessed. The results showed that Bacillus sp. J3 and Lysinibacillus sp. R4 were generally sensitive to antibiotics but resistant to sulfapyridine and ciprofloxacin. Both strains exhibited acid and bile salt resistance in vitro and performed well in extracellular hydrolase tests. J3 demonstrated co-coagulation effects against Aeromonas veronii, Vibrio parahaemolyticus, and Vibrio alginolyticus, with coagulation rates over 35%, while R4 showed the highest co-coagulation rate (47%) against V. alginolyticus. Both strains exhibited strong antibacterial activity, with inhibition zones ranging from 20 to 22.5 mm. Preliminary shrimp farming tests showed that R4 improved shrimp growth and survival rates compared to the control, and its combination with Bacillus coagulans resulted in even greater efficacy. These findings suggest that Lysinibacillus sp. R4 holds promise as a probiotic for enhancing P. vannamei growth, and future research could explore the use of multiple probiotic combinations in aquaculture.
Indexed as
Identifiers
39903286What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.