Evidence map›Paper›PMID 39903250›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Using ultrasound reflection coefficient index and other clinical parameters to predict the risk of progression in adolescents with idiopathic scoliosis (AIS)- a pilot study.

Mahdieh Khodaei, Eric Parent, Lawrence H Le, Sarah Hryniuk Southon, Kyle Stampe, Edmond Lou

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Mahdieh KhodaeiUniversity of Alberta, Edmonton, AB, T6G 2R3, Canada.ORCID 0000-0003-2563-8636
Eric ParentUniversity of Alberta, Edmonton, AB, T6G 2R3, Canada.ORCID 0000-0003-3835-0607
Lawrence H LeUniversity of Alberta, Edmonton, AB, T6G 2R3, Canada.ORCID 0000-0003-1907-1258
Sarah Hryniuk SouthonUniversity of Alberta, Edmonton, AB, T6G 2R3, Canada.ORCID 0000-0002-8244-8057
Kyle StampeUniversity of Alberta, Edmonton, AB, T6G 2R3, Canada.ORCID 0000-0002-4660-9546
Edmond LouUniversity of Alberta, Edmonton, AB, T6G 2R3, Canada. elou@ualberta.ca.ORCID 0000-0002-7531-8377

Funding

Scoliosis Research Society RES0038364Women and Children's Health Research Institute RES0050278
6 · The paper itself

Abstract

purposeTo determine the association of the ultrasound reflection coefficient index and other clinical parameters to predict curve progression in children with AIS.

methodsSixty-six females (13.9 ± 1.5 years old) under observation with baseline Cobb angle (24.4 ± 10.4°) consented and participated. Besides the standard clinical procedures, all participants were scanned by an ultrasound (US) imager in a standing position. All participants had been followed, and the average follow-up visit was 7.5 ± 3.1 months. Five parameters were investigated, including the Cobb angle and the Risser sign measured from the radiographs, and the kyphotic angle (KA), the axial vertebral rotation (AVR), and the reflection coefficient (RC) index measured from the ultrasonographs. The curve was considered progressed when the Cobb angle measured on two consecutive radiographs was increased by more than 5°.

resultsAmong the 5 parameters, the KA, RC index, and Risser sign were found to be significantly associated with progression (p < 0.05). Children who had KA ≤ 38° and RC ≤ 0.06 showed higher chances of progression (62%) versus children with KA > 38° and RC > 0.06.

conclusionThis pilot study showed that curve progression is associated with the Risser sign, KA, and RC index. Other parameters and a more extensive clinical study should be combined to develop a higher-accuracy prediction model.

Indexed as

ScoliosisAdolescentChildDisease ProgressionFemaleHumansPilot ProjectsRadiographyUltrasonographyCurve progressionPredictionScoliosisUltrasound reflection coefficient index

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.