Evidence map›Paper›PMID 39903123›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Spatial propagation of temperate phages within and among biofilms.

James B Winans, Lanying Zeng, Carey D Nadell

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Bacteriophage Therapy AgainstMicroorganisms · 2026
    Review
  4. A look into the virosphere of clouds: A world yet to be explored.Current research in microbial sciences · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

James B WinansDepartment of Biological Sciences, Dartmouth, Hanover, NH 03755.
Lanying ZengDepartment of Biochemistry and Biophysics, Center for Phage Technology, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-8074-5824
Carey D NadellDepartment of Biological Sciences, Dartmouth, Hanover, NH 03755.ORCID 0000-0003-1751-4895

Funding

HOST-MICROBE INTERACTIONST32AI007519 · NIAID · DARTMOUTH COLLEGE · PI DEBORAH A HOGAN · 1997 to 2026
$5.9M
Bacterial and Viral Predator-Prey Dynamics within Bacterial Biofilms at Cellular ResolutionR35GM151158 · NIGMS · DARTMOUTH COLLEGE · PI Carey Nadell · 2023 to 2026
$1.6M
Characterizing Competition Between Virulent and Temperate Phages for Biofilm-Residing Host BacteriaF31AI183523 · NIAID · DARTMOUTH COLLEGE · PI WINANS, JAMES B · 2025 to 2025
$50k
HHS | NIH | National Institute of General Medical Sciences (NIGMS) 1R35GM151158-01Human Frontier Science Program (HFSP) RGY0077/2020NIAID NIH HHS F31 AI183523NIAID NIH HHS T32 AI007519NIGMS NIH HHS R35 GM151158NSF (NSF) 2017879Simons Foundation (SF) 826672
6 · The paper itself

Abstract

Bacteria form groups composed of cells and a secreted polymeric matrix that controls their spatial organization. These groups-termed biofilms-can act as refuges from environmental disturbances and from biotic threats, including phages. Despite the ubiquity of temperate phages and bacterial biofilms, live propagation of temperate phages within biofilms has not been characterized on cellular spatial scales. Here, we leverage several approaches to track temperate phages and distinguish between lytic and lysogenic host infections. We determine that lysogeny within

Indexed as

BacteriophagesBiofilmsEscherichia coliLysogenybiofilmdispersalmatrixphagespatial ecology

Identifiers

PMID39903123
PMCPMC11831127

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.