Evidence map›Paper›PMID 39903108›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Identification of a central regulator of ginkgolide biosynthesis in

Jinfa Du, Zhen Zhao, Lingqi Jin, Lijin Huang, Dian Jin, Xiaoyan Zheng, Qiaolei Wang, Wenbo Xu, Huijun Guo, Xinyue Xing and 6 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jinfa DuDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.ORCID 0000-0002-3063-6881
Zhen ZhaoDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.ORCID 0000-0001-8455-6089
Lingqi JinDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Lijin HuangDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.ORCID 0000-0001-5922-7590
Dian JinDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.ORCID 0009-0002-1325-9073
Xiaoyan ZhengDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Qiaolei WangDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Wenbo XuDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Huijun GuoDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Xinyue XingDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Raphael N AlolgaDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Lam-Son Phan TranDepartment of Plant and Soil Science, Institute of Genomics for Crop Abiotic Stress Tolerance, Texas Tech University, Lubbock, TX 79409.ORCID 0000-0001-9883-9768
Luis Rafael Herrera-EstrellaDepartment of Plant and Soil Science, Institute of Genomics for Crop Abiotic Stress Tolerance, Texas Tech University, Lubbock, TX 79409.ORCID 0000-0001-7936-3856
Ping LiDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Xiaojian YinDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.ORCID 0000-0001-5919-0740
Xu LuDepartment of Pharmacognosy, State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.ORCID 0000-0002-2726-0430

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ginkgolides are secondary metabolites unique to

Indexed as

CyclopentanesGinkgo bilobaGinkgolidesLightOxylipinsSignal TransductionAcetatesGene Expression Regulation, PlantPlant ProteinsPlant RootsPromoter Regions, GeneticTranscription FactorsAcetatesCyclopentanesGinkgolidesjasmonic acidmethyl jasmonateOxylipinsPlant ProteinsTranscription Factorscoordinated regulationGinkgo bilobaginkgolide biosynthesisjasmonatesecondary metabolism

Identifiers

PMID39903108
PMCPMC11831150

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.