Evidence map›Paper›PMID 39902961›Full record

ArticleJournal of virology2025

YTHDF1 and YTHDC1 m

Emily M King, Amanda Midkiff, Karsyn McClain, Sanggu Kim, Amanda R Panfil

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. The mJournal of virology · 2026
    Article
  2. Article
  3. Decoding the role of mNeurochemistry international · 2025
    Review
  4. mGenes to cells : devoted to molecular & cellular mechanisms · 2025
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emily M KingCenter for Retrovirus Research and Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA.
Amanda MidkiffCenter for Retrovirus Research and Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA.
Karsyn McClainCenter for Retrovirus Research and Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA.
Sanggu KimCenter for Retrovirus Research and Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0003-1228-6168
Amanda R PanfilCenter for Retrovirus Research and Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0002-8603-3705

Funding

Role of Inflammation in Tax-mediated TumorigenesisP01CA100730 · NCI · WASHINGTON UNIVERSITY · PI Lee Ratner · 2003 to 2026
$44.8M
Short Trem Research Training for Veterinary StudentsT35OD010977 · OD · OHIO STATE UNIVERSITY · PI Christine A Petersen · 2012 to 2026
$1.1M
NCI NIH HHS P01 CA100730NIH HHS T35 OD010977Ohio Cancer Research (OCR)OSU Center for RNA Biology
6 · The paper itself

Abstract

Human T-cell leukemia virus type 1 (HTLV-1) is a retrovirus responsible for adult T-cell leukemia/lymphoma (ATLL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a progressive neurodegenerative disease. Regulation of viral gene expression plays a key role in viral persistence and pathogenesis. However, the molecular mechanisms underlying this fine-tuned regulation remain poorly understood. Little is known regarding RNA chemical modifications of HTLV-1 RNA and how these affect viral biology and disease development. Post-transcriptional chemical modification of RNA is common in eukaryotes, with N

Indexed as

Basic-Leucine Zipper Transcription FactorsGene Products, taxHuman T-lymphotropic virus 1Nerve Tissue ProteinsRetroviridae ProteinsRNA-Binding ProteinsRNA Splicing FactorsAdenosineGene Expression Regulation, ViralHTLV-I InfectionsHumansRNA, ViralAdenosineBasic-Leucine Zipper Transcription FactorsGene Products, taxHBZ protein, human T-cell leukemia virus type INerve Tissue ProteinsN-methyladenosineRetroviridae ProteinsRNA-Binding ProteinsRNA Splicing FactorsRNA, Viraltax protein, Human T-lymphotrophic virus 1YTHDC1 protein, humanYTHDF1 protein, humanhbzHTLV-1m6ARNAtaxtranscription

Identifiers

PMID39902961
PMCPMC11915865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.