Evidence map›Paper›PMID 39902927›Full record

ArticleAntimicrobial agents and chemotherapy2025

Artemisinin pressure in field isolates can select highly resistant

Lucie Paloque, Luana Mathieu, Marion Laurent, Romain Coppée, Stéphanie Blandin, Pascal Campagne, Jean-Michel Augereau, Lise Musset, Françoise Benoit-Vical

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Global assessment of partial artemisinin resistance: multicenter trial across Kenya, Peru, and Thailand in patients with uncomplicated Plasmodium falciparum malaria.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lucie Paloque *LCC-CNRS, Laboratoire de Chimie de Coordination, Université de Toulouse, CNRS, Toulouse, France.ORCID 0000-0003-0359-3959
Luana Mathieu *Laboratoire de Parasitologie, Centre National de Référence du Paludisme, Pôle Zones Endémiques, WHO Collaborating Center for Surveillance of Antimalarial Drug Resistance, Institut Pasteur de la Guyane, Cayenne, French Guiana.
Marion Laurent *LCC-CNRS, Laboratoire de Chimie de Coordination, Université de Toulouse, CNRS, Toulouse, France.
Romain CoppéeLaboratoire de Parasitologie-Mycologie, Université de Rouen Normandie, Mont-Saint-Aignan, Normandy, France.
Stéphanie BlandinCNRS, Inserm, UPR9022/U1257, Mosquito Immune Responses (MIR), Université de Strasbourg, Strasbourg, France.
Pascal CampagneInstitut Pasteur, Bioinformatics and Biostatistics Hub, Université Paris Cité, Paris, France.
Jean-Michel AugereauLCC-CNRS, Laboratoire de Chimie de Coordination, Université de Toulouse, CNRS, Toulouse, France.
Lise Musset *Laboratoire de Parasitologie, Centre National de Référence du Paludisme, Pôle Zones Endémiques, WHO Collaborating Center for Surveillance of Antimalarial Drug Resistance, Institut Pasteur de la Guyane, Cayenne, French Guiana.
Françoise Benoit-Vical *LCC-CNRS, Laboratoire de Chimie de Coordination, Université de Toulouse, CNRS, Toulouse, France.ORCID 0000-0002-9468-4823

Funding

Agence Nationale de la Recherche (ANR) ANR-10-LABX25-01Agence Nationale de la Recherche (ANR) ANR-11-EQPX-0022Agence Nationale de la Recherche (ANR) ANR-21-CE35-0002-01Regional fund for development Synergie GY0012082
6 · The paper itself

Abstract

Artemisinin resistance, which poses a serious threat to malaria control efforts, is monitored in the field by delayed parasite clearance in patients, elevated parasite survival rate in the ring-stage survival assay, and mutations in the

Indexed as

AntimalarialsArtemisininsDrug ResistancePlasmodium falciparumProtozoan ProteinsHumansMalaria, FalciparumMutationParasitic Sensitivity TestsPhenotypeAntimalarialsartemisininArtemisininsProtozoan Proteinsartemisinin resistancein vitro selectionmalarianon-K13 polymorphism

Identifiers

PMID39902927
PMCPMC11881571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.