Evidence map›Paper›PMID 39902909›Full record

ArticleMicrobiology spectrum2025

Regulation of IL-10 production in dendritic cells is controlled by the co-activation of TLR2 and Mincle by

Ryuhei Sakabe, Kazumasa Onishi, Junko Mochizuki, Takayuki Toshimitsu, Tomoyuki Shimazu, Shigenobu Kishino, Jun Ogawa, Sho Yamasaki, Toshihiro Sashihara

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Preventive effect of heat-killed Lactiplantibacillus plantarum FM8 in an ovalbumin-induced food allergy murine model.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026
    Article
  2. Infection and immunity · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ryuhei SakabeFood Microbiology and Function Research Laboratories, R&D Division, Meiji Co., Ltd., Hachioji, Tokyo, Japan.ORCID 0009-0002-9451-4063
Kazumasa OnishiFermentation Development Research Department Food Development Laboratories, R&D Division, Meiji Co., Ltd., Hachioji, Tokyo, Japan.
Junko MochizukiFood Microbiology and Function Research Laboratories, R&D Division, Meiji Co., Ltd., Hachioji, Tokyo, Japan.
Takayuki ToshimitsuFood Microbiology and Function Research Laboratories, R&D Division, Meiji Co., Ltd., Hachioji, Tokyo, Japan.
Tomoyuki ShimazuFood Microbiology and Function Research Laboratories, R&D Division, Meiji Co., Ltd., Hachioji, Tokyo, Japan.ORCID 0000-0003-3384-6371
Shigenobu KishinoDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.ORCID 0000-0002-4587-2422
Jun OgawaDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.ORCID 0000-0003-2741-621X
Sho YamasakiDepartment of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Toshihiro SashiharaFood Microbiology and Function Research Laboratories, R&D Division, Meiji Co., Ltd., Hachioji, Tokyo, Japan.ORCID 0000-0001-7617-0987

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We showed that

Indexed as

Dendritic CellsInterleukin-10Lactiplantibacillus plantarumLectins, C-TypeMembrane ProteinsToll-Like Receptor 2AnimalsCell LineHumansMiceMice, Inbred C57BLMyeloid Differentiation Factor 88Signal TransductionSyk KinaseClecsf8 protein, mouseIL10 protein, mouseInterleukin-10Lectins, C-TypeMembrane ProteinsMyeloid Differentiation Factor 88Syk KinaseSyk protein, mouseTlr2 protein, mouseToll-Like Receptor 2anti-inflammationinterleukin-10lactic acid bacteriamacrophage inducible C-type lectin receptorphagocytosisToll-like receptor 2

Identifiers

PMID39902909
PMCPMC11878067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.