Evidence map›Paper›PMID 39902883›Full record

ArticleBioengineered2025

Gut microbial dysbiosis associated to diarrheic irritable bowel syndrome can be efficiently simulated in the Mucosal ARtificial COLon (M-ARCOL).

Ophélie Uriot, Charlotte Deschamps, Julien Scanzi, Morgane Brun, Nicolas Kerckhove, Christian Dualé, Elora Fournier, Claude Durif, Sylvain Denis, Michel Dapoigny and 4 more

Abstract read
In one paragraph

Article in Bioengineered, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ophélie UriotUMR 454 MEDIS, Microbiologie Environnement Digestif et Santé, Université Clermont Auvergne - INRAE, Clermont-Ferrand, Puy-de-Dôme,France.
Charlotte DeschampsUMR 454 MEDIS, Microbiologie Environnement Digestif et Santé, Université Clermont Auvergne - INRAE, Clermont-Ferrand, Puy-de-Dôme,France.
Julien ScanziUMR INSERM 1107 NEURO-DOL, Université Clermont Auvergne, Clermont-Ferrand, Puy-de-Dôme,France.
Morgane BrunUMR 454 MEDIS, Microbiologie Environnement Digestif et Santé, Université Clermont Auvergne - INRAE, Clermont-Ferrand, Puy-de-Dôme,France.
Nicolas KerckhoveUMR INSERM 1107 NEURO-DOL, Université Clermont Auvergne, Clermont-Ferrand, Puy-de-Dôme,France.
Christian DualéCIC INSERM 1405, Centre Hospitalo-Universitaire, Clermont-Ferrand, Puy-de-Dôme,France.
Elora FournierUMR 454 MEDIS, Microbiologie Environnement Digestif et Santé, Université Clermont Auvergne - INRAE, Clermont-Ferrand, Puy-de-Dôme,France.
Claude DurifUMR 454 MEDIS, Microbiologie Environnement Digestif et Santé, Université Clermont Auvergne - INRAE, Clermont-Ferrand, Puy-de-Dôme,France.
Sylvain DenisUMR 454 MEDIS, Microbiologie Environnement Digestif et Santé, Université Clermont Auvergne - INRAE, Clermont-Ferrand, Puy-de-Dôme,France.
Michel DapoignyUMR INSERM 1107 NEURO-DOL, Université Clermont Auvergne, Clermont-Ferrand, Puy-de-Dôme,France.
Philippe LangellaMicalis, INRAE, AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, Yvelines,France.
Monique AlricUMR 454 MEDIS, Microbiologie Environnement Digestif et Santé, Université Clermont Auvergne - INRAE, Clermont-Ferrand, Puy-de-Dôme,France.
Lucie Etienne-MesminUMR 454 MEDIS, Microbiologie Environnement Digestif et Santé, Université Clermont Auvergne - INRAE, Clermont-Ferrand, Puy-de-Dôme,France.
Blanquet-Diot StéphanieUMR 454 MEDIS, Microbiologie Environnement Digestif et Santé, Université Clermont Auvergne - INRAE, Clermont-Ferrand, Puy-de-Dôme,France.ORCID 0000-0003-0692-8726

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disorder, with diarrhea-predominant IBS (IBS-D) as the most frequent subtype. The implication of gut microbiota in the disease's etiology is not fully understood.

Indexed as

ColonDiarrheaDysbiosisGastrointestinal MicrobiomeIntestinal MucosaIrritable Bowel SyndromeAdultBioreactorsFecesFemaleFermentationHumansMaleModels, Biologicalbile acidsgut microbiotaIBS-Din vitro gut modelM-ARCOLmucusSCFA

Identifiers

PMID39902883
PMCPMC11796540

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.