Evidence map›Paper›PMID 39902805›Full record

Observational studyHeadache2025

Dyspareunia and pelvic pain in women with chronic migraine: A retrospective, observational analysis.

Liza Smirnoff, Leon S Moskatel

Abstract readObservational Study
In one paragraph

Observational study in Headache, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Liza SmirnoffDepartment of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA.ORCID 0000-0003-1071-515X
Leon S MoskatelDepartment of Neurology and Neurological Sciences, Stanford University, Palo Alto, California, USA.ORCID 0000-0002-8596-9130

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDyspareunia and pelvic pain are commonly comorbid conditions with migraine, with chronic migraine potentially contributing to the exacerbation of sexual dysfunction and pain.

methodsWe conducted a retrospective cohort study of female patients seen at the Stanford Headache Clinic between January 1, 2022, and March 24, 2024, for the management of chronic migraine for dyspareunia and pelvic pain and stratified for comorbidities related to both conditions.

resultsPatients with chronic migraine were overall found to be at higher likelihood of having a comorbid pelvic pain condition after adjusting for age, race-ethnicity, and marital status (adjusted odds ratio [aOR] 2.46; 95% confidence interval [CI]: 2.17-2.79, p < 0.001), with interstitial cystitis (aOR 3.04; 95% CI: 1.98-4.66, p < 0.001), vaginismus (aOR 2.51; 95% CI: 1.29-4.88, p = 0.007), dyspareunia (aOR 1.97; 95% CI: 1.57-2.49, p < 0.001), and vulvodynia (aOR 1.88; 95% CI: 1.04-3.40, p = 0.036) all increased in the chronic migraine population. Furthermore, conditions that are commonly comorbid with migraine, such as irritable bowel syndrome, fibromyalgia, and mood disorders, independently contributed to increased risk of pelvic pain conditions and dyspareunia.

conclusionsConditions that cause pelvic pain and sexual dysfunction in women are disproportionally common in women with chronic migraine and may contribute to disability and difficulties in interpersonal relationships. Early screening for disorders of pelvic pain in patients with chronic migraine and appropriate referrals can improve the quality of life of these patients.

Indexed as

Cystitis, InterstitialDyspareuniaMigraine DisordersPelvic PainVaginismusVulvodyniaAdultComorbidityFemaleHumansMiddle AgedRetrospective Studieschronic migrainedyspareuniapelvic painsexual dysfunctionwomen's health

Identifiers

PMID39902805
PMCPMC12005610

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.