Trial reportPM & R : the journal of injury, function, and rehabilitation2025
Combining procedural and behavioral treatments for chronic low back pain: A pilot feasibility randomized controlled trial.
Trial report in PM & R : the journal of injury, function, and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03520387 (Combined Treatments to Optimize Functional Recovery in Veterans With Chronic Low Back Pain), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Combined Treatments to Optimize Functional Recovery in Veterans With Chronic Low Back Pain
Who cites it
1 citing paper in PubMed.
- Strategies for combining interventional and behavioral therapies in management of chronic low back pain: A scoping review.Interventional pain medicine · 2025Review
Corrections and comments
- Update of
Authors and funding
15 authors.
Funding
Abstract
backgroundIndividual treatments for chronic low back pain (CLBP) have small magnitude effects. Combining different types of treatments may produce larger effects.
objectiveTo (1) assess feasibility of conducting a factorial randomized controlled trial of these treatments; and (2) estimate individual and combined treatment effects of (a) lumbar radiofrequency ablation (LRFA) of the dorsal ramus medial branch nerves (vs. a simulated LRFA control procedure) and (b) Activity Tracker-Informed Video-Enabled Cognitive Behavioral Therapy program for CLBP (AcTIVE-CBT) (vs. an educational control treatment) on back-related disability at 3 months post-randomization.
methodsParticipants (n = 13) were randomized in a 1:1:1:1 ratio in a 2 × 2 factorial randomized controlled trial. Feasibility goals included an enrollment proportion ≥ 30%, a randomization proportion ≥ 80%, and a ≥ 80% proportion of randomized participants completing the 3-month Roland-Morris Disability Questionnaire (RMDQ) primary outcome end point. An intent-to-treat analysis was used.
resultsThe enrollment proportion was 62%, the randomization proportion was 81%, and all randomized participants completed the primary outcome. Though not statistically significant, there was a beneficial, moderate-magnitude effect of LRFA versus control on 3-month RMDQ (-3.25 RMDQ points [95% confidence interval [CI], -10.18 to 3.67]). There was a significant, beneficial, large-magnitude effect of AcTIVE-CBT versus control (-6.29 [95% CI, -10.97 to -1.60]). Though not statistically significant, there was a beneficial, large effect of LRFA+AcTIVE-CBT versus control (-8.37 [95% CI: -21.47, 4.74]).
conclusionWe conclude that it is feasible to conduct a randomized controlled trial combining procedural and behavioral treatments for CLBP. CLINICALTRIALS: gov Registration: https://clinicaltrials.gov/ct2/show/NCT03520387.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.