Evidence map›Paper›PMID 39902575›Full record

ArticleAging cell2025

Nicotinamide Riboside Supplementation Alleviates Testicular Aging Induced by Disruption of Qprt-Dependent NAD

Yining Xu, Huan Wang, Hui Li, Chenlu Wei, Zhenye Zhu, Yanqing Zhao, Jiajia Zhu, Min Lei, Yingpu Sun, Qingling Yang

Abstract read
In one paragraph

Article in Aging cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Restoring NADFrontiers in nutrition · 2026
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yining XuCenter for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Huan WangCenter for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Hui LiCenter for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Chenlu WeiCenter for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhenye ZhuCenter for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yanqing ZhaoCenter for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jiajia ZhuCenter for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Min LeiCenter for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yingpu SunCenter for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0003-3783-6509
Qingling YangCenter for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0002-9187-7961

Funding

National Natural Science Foundation of China 32370917National Natural Science Foundation of China 32470912Scientific Research and Innovation Team of The First Affiliated Hospital of Zhengzhou University QNCXTD2023017
6 · The paper itself

Abstract

Recent studies have shown that disruptions in the nicotinamide adenine dinucleotide (NAD

Indexed as

AgingNADNiacinamidePentosyltransferasesTestisAnimalsDietary SupplementsMaleMicePyridinium CompoundsSpermatogenesisNADNiacinamidenicotinamide-beta-ribosidePentosyltransferasesPyridinium Compoundsmitochondrial functionNAD+ de novo synthesis pathwayspermatogenesistesticular aging

Identifiers

PMID39902575
PMCPMC12151896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.