Evidence map›Paper›PMID 39902438›Full record

ArticleJournal of maxillofacial and oral surgery2025

Oral Vitamin B12 Versus Intra-Nasal Vitamin B12 in Transient Neurosensory Disturbances Following Third Molar Surgery: A Prospective Cohort Study.

Jayanthi Lingaraj, D Prabhu Shankar, Anantanarayanan Parameswaran, T Srinivasa Prasad

Abstract read
In one paragraph

Article in Journal of maxillofacial and oral surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jayanthi LingarajMeenakshi Cleft and Craniofacial Centre, Chennai, Tamil Nadu India.
D Prabhu ShankarDepartment of Oral and Maxillofacial Surgery, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu India.
Anantanarayanan ParameswaranDepartment of Oral and Maxillofacial Surgery, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu India.
T Srinivasa PrasadDepartment of Oral and Maxillofacial Surgery, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The aim was to evaluate the clinical efficacy of intra-nasal vitamin B12 spray compared to oral B12 in the recovery of transient neurosensory disturbances of the lingual nerve post-mandibular third molar surgery. Methods: Thirty patients, who experienced paresthesia of the tongue a day after mandibular third molar surgery, participated in this study. They were randomly divided into two groups: Group 1 (intra-nasal vitamin B12 spray) and Group 2 (oral vitamin B12). Clinical neurosensory tests were conducted at various intervals, and the Fisher's exact test was performed for group comparisons based on recovery. Results: Out of the 30 patients (18 females and 12 males) with transient lingual neurosensory disturbances, after third molar extraction, 15 used the intra-nasal vitamin B12 spray, while the other 15 took oral vitamin B12 tablets. Significant recovery was observed in the nasal group compared to the oral group at POD 16 (p = 0.005) and POD 24 (p = 0.003)." Conclusion: Intra-nasal vitamin B12 sprays were found to be conducive adjuvants to treat transient neurosensory disturbances following third molar surgery. Further studies on its routine application post-neurosensory complications are recommended.

Indexed as

Lingual nerve injuryMandibular third molarNasalOralParesthesiaVitamin B12

Identifiers

PMID39902438
PMCPMC11787116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.