ReviewCureus2025
Evaluating the Effectiveness of MRI Versus CT in Identifying Retroperitoneal Lymph Node Metastasis in Testicular Cancer: A Systematic Review and Meta-Analysis.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Testicular cancer, while rare, is a common malignancy among males aged 15-45 years and often spreads to retroperitoneal lymph nodes. This systematic review and meta-analysis compares the diagnostic accuracy of magnetic resonance imaging (MRI) and computed tomography (CT) in detecting retroperitoneal lymph node metastasis. A comprehensive search was conducted up to January 25, 2024, using PubMed, MEDLINE, Web of Science, and Google Scholar. Studies comparing MRI and CT for detecting retroperitoneal lymph node involvement in adult males with testicular neoplasms were included. Data extraction covered study design, sample size, demographics, imaging techniques, and diagnostic outcomes. The Newcastle-Ottawa Scale was used to assess the risk of bias, and a random-effects model was applied for the meta-analysis. A total of 618 articles were identified, with four meeting the inclusion criteria. The studies reported high sensitivity for both MRI and CT, with MRI sensitivities ranging from 97% to 100% and CT sensitivities from 96% to 100%. Specificity findings were variable, with some studies suggesting similar or slightly higher values for MRI. Meta-analysis of three studies revealed no significant difference between MRI and CT in detecting retroperitoneal lymph node metastasis, with an odds ratio of 1.00 (95% CI: 0.54 to 1.86) and minimal heterogeneity (I² = 0%). These findings suggest both MRI and CT demonstrate comparable diagnostic accuracy in detecting retroperitoneal lymph node metastasis in testicular cancer. While MRI avoids ionizing radiation, it requires expert interpretation and is more costly, limiting its accessibility in some settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.