Evidence map›Paper›PMID 39902006›Full record

ArticleCureus2025

A Rare Case of Methamphetamine-Induced Diffuse Gastrointestinal Ischemia.

Nicole Johnsen, Andrew Chang, Kelley Chuang, Satya Patel, Simon Wu

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicole JohnsenInternal Medicine, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, USA.
Andrew ChangInternal Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, USA.
Kelley ChuangInternal Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, USA.
Satya PatelInternal Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, USA.
Simon WuInternal Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methamphetamine is a widely used substance known for cardiovascular and neurological complications; however, its gastrointestinal effects remain poorly understood. While rare, methamphetamine-induced gastrointestinal ischemia has high morbidity and mortality rates, with limited case reports in the literature. We present a case of a 48-year-old man with a history of gastroesophageal reflux disease, alcohol use disorder in remission, and previously documented methamphetamine use who presented with two weeks of episodic abdominal pain, nausea, and hematemesis. Significant laboratory and imaging findings included acute anemia, urine toxicology confirming the presence of amphetamines, and computed tomography imaging showing wall thickening in the distal esophagus and stomach. On endoscopy, he was found to have diffuse ulcerations in the distal esophagus and post-pyloric region with pathology indicative of methamphetamine-induced gastrointestinal ischemia. This case highlights the importance of considering amphetamine-induced gastrointestinal ischemia in patients with stimulant use disorders who present with acute abdominal symptoms. Early recognition of this etiology can guide targeted counseling and management to improve outcomes.

Indexed as

clinical methamphetamine effectsdrug-induced ischemiaextensive gi ulcerationgastrointestinal ischemiamethamphetaminerare cause of acute abdominal painsubstance use

Identifiers

PMID39902006
PMCPMC11788447

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.