Evidence map›Paper›PMID 39901976›Full record

ArticleFrontiers in health services2024

Economic evaluation of a strategy to shorten the time to surgery with neuraxial anaesthesia compared with usual clinical practice in patients on chronic antiplatelet therapy with a proximal femur fracture.

Claudia Erika Delgado-Espinoza, Rosa Maria Antonijoan, Ignasi Gich, Rafael Anaya, Mireia Rodriguez, Angélica Millan, Jordi Llorca, Gemma Usua, Ana Ruiz, Angela Merchán-Galvis and 1 more

Abstract read
In one paragraph

Article in Frontiers in health services, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Claudia Erika Delgado-EspinozaClinical Pharmacology Service, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Rosa Maria AntonijoanClinical Pharmacology Service, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Ignasi GichClinical Epidemiology and Public Health Service, Fundació Institut de Recerca Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Rafael AnayaAnaesthesiology Service, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Mireia RodriguezAnaesthesiology Service, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Angélica MillanOrthopedic and Traumatology Surgery Service, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Jordi LlorcaAnaesthesiology Service, Xarxa Assistencial Universitària de Manresa, Barcelona, Spain.
Gemma UsuaAnaesthesiology Service, Hospital de la Vall d'Hebron, Barcelona, Spain.
Ana RuizAnaesthesiology Service, Hospital Clinic de Barcelona, Barcelona, Spain.
Angela Merchán-GalvisDepartamento de Medicina Social y Salud Familiar, Universidad del Cauca, Popayan, Colombia.
Maria Jose Martinez-ZapataCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBER of Epidemiology and Public Health), Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Before implementing a new health care strategy, it is important to assess effectiveness but also to perform an economic evaluation. The goal of the present study was to perform a comparative economic evaluation of a new strategy aimed at using proposed implementation of the Plateletworks guidance (measurement of platelet function) with usual practice (delayed time to surgery) in patients on chronic antiplatelet treatment and scheduled for surgery with neuraxial anaesthesia due to proximal femur fracture. Methods: This is an economic evaluation carried out alongside a randomised controlled clinical trial at four centres in Spain. Patients were randomised to undergo either early platelet function-guided surgery (experimental group) or delayed surgery (control group). As AFFEcT trial results demonstrated significative difference between groups in the primary efficacy endpoint, the median time to surgery, a cost-effectiveness analysis was performed. Direct costs associated with hospitalisation until one-month post-discharge were considered and measured from a hospital perspective. All costs were reported in euros. Analyses were performed on a per protocol basis. Effectiveness outcome measures were the incremental cost and incremental cost per reduction in days to surgery. A deterministic sensitivity analysis was implemented to quantify uncertainty. Results: A total of 156 patients were randomized to the two groups ( Conclusion: For patients on chronic antiplatelet treatment scheduled to undergo surgery for proximal femur fracture, an individualised strategy guided by a platelet function testing is a cost-saving and cost-effective strategy.

Indexed as

economic evaluationfemur fractureneuraxial anaesthesiaplatelet function testrandomised clinical trial

Identifiers

PMID39901976
PMCPMC11788385

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.