ReviewJournal of pain research2025
Effect of Genicular Nerve Block (GNB) on Pain in Lesions of the Knee Joint: A Meta-Analysis of Randomized Controlled Trials.
Review in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07174167 (Effectiveness of Genicular Nerve Block on Pain and Disability in Chronic Knee Osteoarthritis), which is not on this map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Genicular Nerve Block on Pain and Disability in Chronic Knee Osteoarthritis: A Randomized Controlled Trial
Who cites it
2 citing papers in PubMed.
- Effectiveness of genicular nerve block on pain and disability in chronic knee osteoarthritis: a randomized double blinded placebo controlled trial.Clinical rheumatology · 2026Trial
- Genicular Nerve Block as an Effective Treatment for Knee Pain: Addressing Variability and Enhancing Meta-Analysis Reliability [Letter].Journal of pain research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To explore the effect of genicular nerve block (GNB) on pain in lesions of the knee joint. Computerized searches of randomized controlled trials were conducted in PubMed, EMbase, Cochrane Library, and Web of Science, with a search time frame until January 2024. Methodological and experimental quality was assessed using the risk of bias assessment tool recommended by the Cochrane Handbook. A meta-analysis was conducted of the pain score (as the primary outcome measure) using Review Manager 5.4 and Stata 17. Thirteen studies involving a total of 731 patients were ultimately included. In the comparison of GNB and non-GNB, the analysis results of analgesic effects at all visits showed [SMD=-0.51, 95% CI (-0.89, -0.14)]. Analysis of analgesic effects at a visit at 1 month showed [SMD=-0.79, 95% CI (-1.55, -0.02)]. Subgroup analysis for the control group showed [SMD=-4.07,9 5% CI (-4.10, -1.84)]. Currently, available evidence suggests that GNB may be an effective analgesic therapy and superior to other regimens in the treatment of lesions of the knee joint.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.