Evidence map›Paper›PMID 39901924›Full record

ArticleIn silico pharmacology2025

Multi-scale computational modeling to identify novel chemical scaffolds as trehalose-6-phosphate phosphatase inhibitors to combat

Sara Noor, Mohammad Abdullah Aljasir, Maryam Bashir, Kalsoom Khan, Sajjad Ahmad, Syed Ainul Abideen, Saifullah Khan, Farhan Siddique, Hamza Ahmad, Khudija Ghani and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In silico pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sara Noor *Department of Health and Biological Sciences, Abasyn University, Peshawar, 25000 Pakistan.
Mohammad Abdullah AljasirDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia.
Maryam Bashir *Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Bahauddin Zakriya University, Multan, 60800 Pakistan.
Kalsoom KhanDepartment of Health and Biological Sciences, Abasyn University, Peshawar, 25000 Pakistan.
Sajjad AhmadDepartment of Health and Biological Sciences, Abasyn University, Peshawar, 25000 Pakistan.
Syed Ainul AbideenDepartment of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, People's Republic of China.
Saifullah KhanInstitute of Biotechnology and Microbiology, Bacha Khan University, Charsadda, Pakistan.
Farhan SiddiqueDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Bahauddin Zakriya University, Multan, 60800 Pakistan.
Hamza AhmadCenter of Biotechnology and Microbiology, University of Peshawar, Peshawar, 25000 Pakistan.
Khudija GhaniSarhad Institute of Allied Health Sciences, Sarhad University of Science and Information Technology, Peshawar, 25000 Pakistan.
Madiha IqbalDepartment of Health and Biological Sciences, Abasyn University, Peshawar, 25000 Pakistan.
Muhammad IrfanASRT, Inc., Atlanta, GA USA.
Abbas KhanDepartment of Biological Sciences, School of Medical and Life Sciences, Sunway University, Jalan Universiti, Bandar Sunway, 47500 Selangor Darul Ehsan Malaysia.
Dong-Qing WeiZhongjing Research and Industrialization Institute of Chinese Medicine, Zhongguancun Scientific Park, Nayang, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Supplementary Information: The online version contains supplementary material available at 10.1007/s40203-025-00309-5.

Indexed as

Burkholderia pseudomalleiDensity functional theoryMolecular docking simulationStructure-based virtual screening

Identifiers

PMID39901924
PMCPMC11787118

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.