Evidence map›Paper›PMID 39901722›Full record

ArticleSleep2025

Circadian phase in high-school students: weekday-weekend shifts and relationships to other sleep/circadian characteristics.

Brant P Hasler, Nina Oryshkewych, Meredith L Wallace, Duncan B Clark, Greg J Siegle, Daniel L Buysse

Abstract read
In one paragraph

Article in Sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brant P HaslerDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0002-3123-1106
Nina OryshkewychDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0009-0008-9332-1810
Meredith L WallaceDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0003-3951-890X
Duncan B ClarkDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Greg J SiegleDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0002-1420-8975
Daniel L BuysseDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0002-3288-1864

Funding

Proximal prospective associations between circadian alignment, reward function and alcohol use in adolescentsR01AA025626 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HASLER, BRANT P. · 2017 to 2021
$2.8M
NIAAA NIH HHS R01 AA025626NIH HHS R01AA025626
6 · The paper itself

Abstract

STUDY

objectivesIn a sample of high-school students, (1) to characterize within-person changes in sleep and circadian characteristics from school nights to weekend nights, (2) to examine whether later circadian phase relates to weekday-weekend changes in sleep/circadian characteristics, and (3) to examine correlations between biological and proxy measures of circadian phase.

methodsSample included 95 high-school students reporting at least one drink of alcohol in their lifetime. Participants completed baseline self-report measures, wrist actigraphy for 8 days, and two overnight laboratory visits (Thursday and Sunday) for salivary melatonin sample collection. Circadian phase was calculated as the dim light melatonin onset (DLMO; 4 pg/mL threshold). Proxy circadian phase measures included the Composite Scale of Morningness (CSM), Munich Chronotype Questionnaire (MCTQ), and actigraphy-based midsleep.

resultsOther than nap duration, all examined actigraphy-based sleep characteristics, DLMO, and DLMO-sleep phase angles showed weekday-weekend differences (adjusted p-value < .05). Later mean DLMO was associated with larger weekday-weekend changes in total sleep time (b = 0.39, padjusted = .010). CSM and actigraphy-based midsleep showed small-to-moderate (rho = ~0.3) and moderate (rho = ~0.5) correlations with DLMO, respectively, but chronotype based on the MCTQ was not correlated with DLMO.

conclusionsIn the largest published sample to date, circadian phase substantially shifted from the school week to weekend, underscoring the "social jetlag" imposed by early school start times. Similarly, teens with the latest circadian phase exhibited the greatest weekend catch-up sleep. Finally, perhaps due to the instability of circadian phase in this context, self-reported proxies for circadian timing were poor approximations of biological circadian phase.

Indexed as

Circadian RhythmSleepStudentsActigraphyAdolescentFemaleHumansMaleMelatoninSalivaSchoolsSelf ReportSurveys and QuestionnairesTime FactorsMelatoninactigraphyadolescentschronotypecircadian misalignmentdim light melatonin onsetsocial jetlag

Identifiers

PMID39901722
PMCPMC11985389

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.