Evidence map›Paper›PMID 39901677›Full record

ReviewRecent advances in anti-infective drug discovery2025

Novel Therapeutic Approaches Emerging in the Field of Onychomycosis.

Gurisha Garg, Raj Kamal, Sonakshi Garg, Preeti Patel, Balak Das Kurmi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Recent advances in anti-infective drug discovery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gurisha GargDepartment of Pharmaceutical Quality Assurance, ISF College of Pharmacy, GT Road, Moga, Punjab, 142001, India.
Raj KamalDepartment of Pharmaceutical Quality Assurance, ISF College of Pharmacy, GT Road, Moga, Punjab, 142001, India.
Sonakshi GargDepartment of Pharmaceutical Quality Assurance, ISF College of Pharmacy, GT Road, Moga, Punjab, 142001, India.
Preeti PatelDepartment of Pharmaceutical Chemistry, ISF College of Pharmacy, GT Road, Moga, Punjab, 142001, India.
Balak Das KurmiDepartment of Pharmaceutics, ISF College of Pharmacy, GT Road, Moga, Punjab, 142001, India.ORCID 0000-0001-8470-6622

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Onychomycosis is regarded as one of the most common and least concerned fungal problems. Although various treatment approaches have been well-established, still treatment strategies suffer from certain drawbacks, so there is a need to discuss novel therapies that could ultimately eliminate all the conventional barriers. It is a nail infection that begins in the toenail and spreads, causing significant negative impacts on patients' quality of life. The purpose of this work was to highlight the limitations of conventional treatments and shed light on novel therapies for managing onychomycosis. A comprehensive review on existing topical and systemic therapies was conducted, with a focus on their drawbacks, such as recurrence and lower efficacy. This review aimed to explore the increasing prevalence of onychomycosis, which poses a serious health issue; however, the advent of nanobased drug delivery systems offers hope for more effective management of this prevalent disease. These systems could potentially overcome the limitations of conventional treatments, thereby improving patient outcomes.

Indexed as

Antifungal AgentsDrug Delivery SystemsFoot DermatosesOnychomycosisAdministration, TopicalHumansQuality of LifeAntifungal Agentsmycoses.nanocarrieronychocryptosisOnychomycosissuperficial onychomycosistotal dystrophic onychomycosis

Identifiers

PMID39901677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.