Evidence map›Paper›PMID 39901066›Full record

ArticleBMC genomics2025

Transcriptome-wide identification and characterization of WUSCHEL-related homeobox (WOX) gene family in Pinus yunnanensis.

Junfei Xu, Zhaoliu Hu, Sili Chen, Junrong Tang, Lin Chen, Peizhen Chen, Nianhui Cai, Yulan Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Genome-Wide Identification of theInternational journal of molecular sciences · 2026
    Article
  2. Genome-Wide Characterization of thePlants (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Junfei XuKey Laboratory of National Forestry and Grassland Administration on Biodiversity Conservation in Southwest China, Southwest Forestry University, Kunming, China.
Zhaoliu HuKey Laboratory of National Forestry and Grassland Administration on Biodiversity Conservation in Southwest China, Southwest Forestry University, Kunming, China.
Sili ChenKey Laboratory of National Forestry and Grassland Administration on Biodiversity Conservation in Southwest China, Southwest Forestry University, Kunming, China.
Junrong TangKey Laboratory of National Forestry and Grassland Administration on Biodiversity Conservation in Southwest China, Southwest Forestry University, Kunming, China.
Lin ChenKey Laboratory of National Forestry and Grassland Administration on Biodiversity Conservation in Southwest China, Southwest Forestry University, Kunming, China.
Peizhen ChenKey Laboratory of National Forestry and Grassland Administration on Biodiversity Conservation in Southwest China, Southwest Forestry University, Kunming, China.
Nianhui CaiKey Laboratory of National Forestry and Grassland Administration on Biodiversity Conservation in Southwest China, Southwest Forestry University, Kunming, China.
Yulan XuKey Laboratory of National Forestry and Grassland Administration on Biodiversity Conservation in Southwest China, Southwest Forestry University, Kunming, China. xuyulan@swfu.edu.cn.

Funding

Joint Funds of the Basic Agricultural Research of Yunnan Province 202301BD070001-035National Natural Science Foundation of China 32360381the Key Project of Joint Funds of the Basic Agricultural Research of Yunnan Province 202301BD070001-152the Scientific Research Fund project of Education Department of Yunnan Province 2023Y0731the Yunnan Provincial First-Class Discipline Construction Fund for Forestry at Southwest Forestry University LXXK-2024Z07Yunnan Province Ten Thousand People Plan Youth Top Talent Project Funding YNWR-QNBJ-2019-075
6 · The paper itself

Abstract

WUSCHEL-related homeobox (WOX), a specific gene family in plants, plays a critical role during stem cell regulation, plant regeneration and upgrowth. However, our understanding of WOX functions in conifers is limited compared to angiosperms. To address this gap, we investigated the presence, expression profiles and protein characteristics of WOX gene in P. yunnanensis. Our findings revealed that 10 PyWOX genes were dispersed across three existing clades, and their expression profiles were presented in specific developmental stages and tissues. The ancient-clade members (PyWOX13, PyWOXG, PyWOXA) exhibited constitutive expressions in most tissues and developmental stages, indicating that they are the oldest and conserved WOX genes. Members of the intermediate-clade (PyWOXB, PyWOXE) were primarily expressed during callus formation and seed germination, suggesting a role in promoting embryogenesis and plant regeneration. Most members of WUS-clade (PyWUS, PyWOX3, PyWOX4, PyWOX5, PyWOXX) showed high transcripts level in cluster buds, which may be related to meristematic development and the formation of axillary meristems. The self-activation assay demonstrated that PyWOX4 has transcriptional activation activity. Our study also suggested that there were highly conserved and clear orthologs of WOX genes present in Pinus. Together, these findings provide a foundation for further clarifying the function and regulatory mechanism of WOX genes in P. yunnanensis growth and development.

Indexed as

Genes, HomeoboxHomeodomain ProteinsMultigene FamilyPinusPlant ProteinsTranscriptomeGene Expression ProfilingGene Expression Regulation, PlantPhylogenyHomeodomain ProteinsPlant ProteinsExpression profileGrowth and developmentPhylogenyPinus yunnanensisWUSCHEL-related homeobox

Identifiers

PMID39901066
PMCPMC11789396

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.