ArticleBMC genomics2025
Genome-wide identification and characterization of WRKYs family involved in responses to Cylindrocarpon destructans in Panax notoginseng.
Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Medicinal-plant immunity and specialized metabolism in plant-pathogen interactions: mechanisms and applications.Planta · 2026Review
- Identification of CAMTA transcription factors and functional analysis of OsCAMTA4 in rice blast and salt stress.Planta · 2026Article
- Genome‑wide analysis of the CaWRKY transcription factors reveals CaWRKY28 as a candidate gene for cold tolerance breeding in Coffea arabica L.BMC plant biology · 2026Article
- Cloning ofGenes · 2026Article
- Identification and functional characterization of a novel gene conferring root rot resistance in Panax Notoginseng.BMC plant biology · 2026Article
- Melatonin-inducedFrontiers in plant science · 2026Article
- Genome-wide identification, characterization, and expression profiling of TIFY family members in Panax notoginseng.BMC genomics · 2025Article
- Advances in WRKY regulation of immune responses in medicinal plants.Frontiers in plant science · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundWRKY transcription factors (TFs) are key regulators of plant responses to biotic and abiotic stresses. Previous studies demonstrated that the role of WRKY TFs play in the disease resistance of Panax notoginseng, the causal agent of root rot disease. However, comprehensive genome-wide analyses of WRKY genes in this species remain scarce.
resultWe identified 79 WRKY genes in the P. notoginseng genome, classifing them into three groups based on structural features and phylogenetic relationships: Class I (14 genes), Class II (55 genes), and Class III (10 genes). Of these, 58 PnWRKY genes were mapped to the P. notoginseng chromosomes and showed collinearity with Arabidopsis thaliana, Daucus carota, and three Solanaceae species. Expression analysis revealed that 53 PnWRKY genes were actively transcribed across various tissues, including roots, flowers, stems, rhizomes, and different root parts. Furthermore, PnWRKY genes responded to Cylindrocarpon destructans infection and were induced by jasmonic acid (JA) and salicylic acid (SA). Notably, the ectopic expression of PnWRKY35 in tobacco enhanced resistance to C. destructans, accompanied by increased levels of gibberellins (GA
conclusionThis study demonstrated that the WRKY family in P. notoginseng plays a significant role in resistance to root rot disease. PnWRKY genes are responsive to MeJA and SA induction as well as C. destructans infection. Moreover, ectopic expression of PnWRKY35 activates multiple plant disease resistance pathways, increases phytohormone levels, and enhance resistance to C. destructans. These findings provide a foundation for future exploration of the mechanism underlying P. notoginseng resistance to root rot disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.