ArticleScientific reports2025
Two chromatographic methods for analyzing paracetamol in spiked human plasma with its toxic metabolite, N-acetyl parabenzoquinone imine and its antidote, N-acetyl-L-cysteine.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Novel eco-friendly spectrophotometric determination of potential combination silodosin and darifenacin hydrobromide in bulk and pharmaceutical formulations.BMC chemistry · 2026Article
- Molybdenum disulfide-grafted carbon nanotubes for the electrochemical detection of acetaminophen with ultra-sensitivity.RSC advances · 2026Article
- Saffron sporopollenin modified with graphene oxide for efficient extraction of acetaminophen from serum using deep eutectic solvent prior to HPLC.Scientific reports · 2025Article
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Abstract
Acetaminophen, also known as paracetamol (APAP), is a highly utilized pharmaceutical agent on a global scale, particularly in the field of pediatrics. Regrettably, an overdose of APAP, resulting from the predominant oxidation, has the potential to trigger acute liver injury. The study's goal was to find an easy, accurate, and selective way to measure APAP, N-acetyl para benzoquinone imine (NAPQI) (an APAP metabolite that is harmful), and N-acetyl-L-cysteine (NAC) (an antidote). Two different chromatographic methods were used. The HPTLC method, which used silica gel 60 F
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