Evidence map›Paper›PMID 39900921›Full record

ArticleNature communications2025

USP5 stabilizes YTHDF1 to control cancer immune surveillance through mTORC1-mediated phosphorylation.

Na Shao, Lei Xi, Yangfan Lv, Muhammad Idris, Lin Zhang, Ya Cao, Jingyi Xiang, Xi Xu, Belinda X Ong, Qiongyi Zhang and 4 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. mJournal for immunotherapy of cancer · 2025
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Na Shao *Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), The Second Affiliated Hospital, Chongqing Medical University, Chongqing, PR China.
Lei Xi *College of Biological and Food Engineering, Hubei Minzu University, Enshi, PR China.
Yangfan Lv *Department of Pathology, Xinqiao Hospital, Third Military Medical University, Chongqing, PR China.
Muhammad IdrisInstitute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.ORCID http://orcid.org/0000-0002-5625-0426
Lin ZhangKey Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), The Second Affiliated Hospital, Chongqing Medical University, Chongqing, PR China.
Ya CaoDepartment of Pathology, Xinqiao Hospital, Third Military Medical University, Chongqing, PR China.
Jingyi XiangKey Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), The Second Affiliated Hospital, Chongqing Medical University, Chongqing, PR China.
Xi XuDepartment of Pathology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, PR China.
Belinda X OngInstitute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.ORCID http://orcid.org/0000-0002-2864-1905
Qiongyi ZhangInstitute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.
Xu PengInstitute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.
Xiaoyan YueInstitute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.
Feng XuInstitute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore. Xufeng95@gmail.com.ORCID http://orcid.org/0000-0003-2016-7521
Chungang LiuKey Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), The Second Affiliated Hospital, Chongqing Medical University, Chongqing, PR China. liuchungang@zju.edu.cn.ORCID http://orcid.org/0000-0001-7413-5934

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32101024National Natural Science Foundation of China (National Science Foundation of China) 81972297National Natural Science Foundation of China (National Science Foundation of China) 82372748
6 · The paper itself

Abstract

The N

Indexed as

Mechanistic Target of Rapamycin Complex 1NeoplasmsRNA-Binding ProteinsUbiquitin-Specific ProteasesAnimalsB7-H1 AntigenCell Line, TumorGene Expression Regulation, NeoplasticHEK293 CellsHumansMicePhosphorylationProtein StabilityUbiquitinationB7-H1 AntigenCD274 protein, humanMechanistic Target of Rapamycin Complex 1RNA-Binding ProteinsUbiquitin-Specific ProteasesYTHDF1 protein, human

Identifiers

PMID39900921
PMCPMC11791202

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.