Evidence map›Paper›PMID 39900582›Full record

ArticleScientific reports2025

Polypharmacy and self-medication among older adults in Indian urban communities-a cross-sectional study.

Saibal Das, Pavithra Gnanavel, Shalini Smanla, Anku Moni Saikia, Shilpi Mishra, Shweta Khare, S Arun Murugan, Vadanere Nidhi Prakash, Parimita Roychoudhury, Ishteyaque Ahmad and 17 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Observational
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Saibal Das *Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden. saibal.das@ki.se.
Pavithra Gnanavel *Department of Community Medicine, Government Medical College, Omandurar Government Estate, Chennai, India.
Shalini Smanla *Department of Community Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Anku Moni Saikia *Department of Community Medicine, Dhubri Medical College and Hospital, Dhubri, India.
Shilpi Mishra *Department of Pharmacology, Netaji Subhas Medical College and Hospital, Patna, India.
Shweta Khare *Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
S Arun MuruganDepartment of Community Medicine, Government Medical College, Omandurar Government Estate, Chennai, India.
Vadanere Nidhi PrakashDepartment of Community Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Parimita RoychoudhuryDepartment of Community Medicine, Dhubri Medical College and Hospital, Dhubri, India.
Ishteyaque AhmadDepartment of Pharmacology, Netaji Subhas Medical College and Hospital, Patna, India.
Vishal DiwanDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
J RajeshDepartment of Community Medicine, Kilpauk Medical College, Chennai, India.
K Sathish KumarDepartment of Community Medicine, Government Medical College, Omandurar Government Estate, Chennai, India.
Jugal KishoreDepartment of Community Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Namita SrivastavaDepartment of Community Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Sabrina YasminDepartment of Community Medicine, Dhubri Medical College and Hospital, Dhubri, India.
Mahmuda NasrinDepartment of Community Medicine, Dhubri Medical College and Hospital, Dhubri, India.
Rinku BorahDepartment of Community Medicine, Dhubri Medical College and Hospital, Dhubri, India.
Mandeep Sarma BasisthaDepartment of Pharmacology, Nagaon Medical College Hospital, Nagaon, India.
Chetanjit BaruahDepartment of Community Medicine, Tinsukia Medical College and Hospital, Tinsukia, India.
Manoj KalitaIndian Council of Medical Research - Centre for Aging and Mental Health, Kolkata, India.
Shambo Samrat SamajdarDepartment of Pharmacology, JNM Medical College and Hospital, Nadia, India.
Jerin Jose CherianDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Ashish PathakDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Samiran PandaIndian Council of Medical Research, New Delhi, India.
Santanu Kumar TripathiJagannath Gupta Institute of Medical Sciences and Hospital, Kolkata, India.
Cecilia Stålsby LundborgDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Older adults are vulnerable to unsafe medication practices. This cross-sectional study estimated the prevalence and factors of polypharmacy and self-medication among 600 older adults from six Indian cities. The updated Screening Tool of Older Persons' Prescriptions and Screening Tool to Alert to Right Treatment criteria (version 3) were used. Knowledge, attitudes, and reported practices regarding self-medication were assessed. Descriptive statistics, binary logistic regression, and multivariable analysis were used. The prevalence of polypharmacy was 33.7% (95% CI 29.9-37.6%), with significant associations to multiple comorbidities [adjusted odds ratio (aOR) 2.5 (95% CI 1.1-4.1)], recent transition of care [aOR 3.3 (95% CI 1.4-5.7)], and recent hospitalization [aOR 4.6 (95% CI 2-7.7)]. The proportions of prescriptions with potentially inappropriate medications and potential prescribing omissions were 28.8% (95% CI 25.2-32.6%) and 20.3% (95% CI 17.2-23.8%), respectively. The prevalence of self-medication was 19.7% (95% CI 16.6-23.1%), associated with factors, such as staying alone [aOR 4.5 (95% CI 2.4-6.6)], multiple comorbidities [aOR 3 (95% CI 1.4-6.7)], and recent hospitalization [aOR 4.8 (95% CI 1.5-8)]. Among those who self-medicated, 65.3% lacked knowledge of self-medication, 50% did not comprehend the risks, and 40.7% reported unsafe self-medication practices. The findings emphasize interventions' necessity for promoting safe medication use in older adults.

Indexed as

PolypharmacySelf MedicationUrban PopulationAgedAged, 80 and overComorbidityCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansIndiaMaleMiddle AgedPrevalenceOlder adultsPolypharmacyPotentially inappropriate medications (PIMs)Potential prescribing omissions (PPOs)Screening tool of older persons’ prescriptions and screening tool to alert to right treatment (STOPP-START)Self-medication

Identifiers

PMID39900582
PMCPMC11791031

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.