Evidence map›Paper›PMID 39900419›Full record

ArticleBMJ open2025

mHealth Intervention for Dementia Prevention through lifestyle Optimisation (MIND-PRO) in a primary care setting: protocol for a randomised controlled trial in people with low SES and/or migration background.

Anne Roos van der Endt, Marieke P Hoevenaar-Blom, Henrike Galenkamp, Martien J H Kas, Esther van den Berg, Ron Handels, Eric P Moll van Charante, Edo Richard

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anne Roos van der EndtDepartment of Public and Occupational Health, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands j.r.vanderendt@amsterdamumc.nl.ORCID http://orcid.org/0009-0009-1161-5338
Marieke P Hoevenaar-BlomDepartment of Public and Occupational Health, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
Henrike GalenkampDepartment of Public and Occupational Health, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
Martien J H KasInstitute for Evolutionary Life Sciences, University of Groningen, Groningen, The Netherlands.
Esther van den BergDepartment of Neurology and Alzheimer Center, Erasmus MC, Rotterdam, The Netherlands.
Ron HandelsAlzheimer Centre Limburg, Department of Psychiatry and Neuropsychology, School of Mental Health and Neurosicences, Maastricht University, Maastricht, The Netherlands.
Eric P Moll van Charante *Department of Public and Occupational Health, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
Edo Richard *Department of Public and Occupational Health, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Mobile Health (mHealth) Intervention for Dementia Prevention through lifestyle Optimisation (MIND-PRO) study addresses the increasing prevalence of dementia among populations with lower socio-economic status (SES) and/or a migration background. The study aims to evaluate the effectiveness and implementation of an mHealth intervention designed for self-managing lifestyle modifications with remote coaching to reduce dementia risk factors. METHODS AND ANALYSIS: This prospective randomised open-label blinded end point (PROBE) trial follows a type 2 hybrid effectiveness-implementation design with a 12-month intervention period. It aims to recruit 692 participants in Dutch primary care. Entry criteria include age 50-75 years, low SES and/or migration background, one or more dementia risk factors (hypertension, dyslipidaemia, diabetes mellitus, physical inactivity, smoking, depression and overweight) or manifest cardiovascular disease and possession of a smartphone. Participants are randomised to a coach-supported, interactive app facilitating self-management of dementia risk factors or to a control app with static health information. The primary effectiveness outcome is a composite score of systolic blood pressure, non-high-density lipoprotein cholesterol and body mass index. Implementation outcomes include coverage, adoption, acceptability, appropriateness, feasibility, fidelity, costs and sustainability of the intervention. Secondary outcomes include the Cardiovascular Risk Factors, Ageing and Dementia risk score and its individual risk factors, and disability, physical activity, depressive symptoms, cognitive functioning and daily distance moved. ETHICS AND DISSEMINATION: The MIND-PRO trial is funded by the Netherlands Organisation for Health Research and Development (ZonMw, grant number 10510032120004) and approved by the Ethics Committee of Amsterdam UMC (reference: METC 2023.0770). Results are expected in 2026 and will be submitted for publication in a peer-reviewed journal, and presented at scientific conferences. TRIAL REGISTRATION NUMBER: ISRCTN92928122.

Indexed as

DementiaLife StyleAgedFemaleHumansMaleMiddle AgedMobile ApplicationsNetherlandsPrimary Health CareProspective StudiesRandomized Controlled Trials as TopicRisk FactorsTelemedicinecardiovascular diseasedementiaeHealthresearch designrisk management

Identifiers

PMID39900419
PMCPMC11956295

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.