Evidence map›Paper›PMID 39900350›Full record

ArticleACS applied bio materials2025

The Compression-Dominated Ultrasound Response of Poly(

Julia Blöck, Hongchen Li, Gonzalo Collado-Lara, Klazina Kooiman, Anne Rix, Junlin Chen, Christopher Hark, Harald Radermacher, Céline Porte, Fabian Kiessling

Abstract read
In one paragraph

Article in ACS applied bio materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Julia BlöckInstitute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Forckenbeckstraße 55, 52070 Aachen, Germany.
Hongchen LiBiomedical Engineering, Department of Cardiology, Cardiovascular Institute, Erasmus MC University Medical Center Rotterdam, Dr. Molewaterplein 40, 3015 GD Rotterdam , The Netherlands.
Gonzalo Collado-LaraBiomedical Engineering, Department of Cardiology, Cardiovascular Institute, Erasmus MC University Medical Center Rotterdam, Dr. Molewaterplein 40, 3015 GD Rotterdam , The Netherlands.
Klazina KooimanBiomedical Engineering, Department of Cardiology, Cardiovascular Institute, Erasmus MC University Medical Center Rotterdam, Dr. Molewaterplein 40, 3015 GD Rotterdam , The Netherlands.ORCID 0000-0002-0607-4989
Anne RixInstitute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Forckenbeckstraße 55, 52070 Aachen, Germany.
Junlin ChenInstitute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Forckenbeckstraße 55, 52070 Aachen, Germany.
Christopher HarkInstitute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Forckenbeckstraße 55, 52070 Aachen, Germany.ORCID 0009-0006-4233-588X
Harald RadermacherInstitute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Forckenbeckstraße 55, 52070 Aachen, Germany.
Céline PorteInstitute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Forckenbeckstraße 55, 52070 Aachen, Germany.
Fabian KiesslingInstitute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Forckenbeckstraße 55, 52070 Aachen, Germany.ORCID 0000-0002-7341-0399

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The process of locally increasing the permeability of cell membranes or cell layers is referred to as sonoporation or sonopermeation, respectively, and opens up perspectives for drug delivery in cancer treatment by facilitating enhanced local drug accumulation. These effects are mediated by ultrasound-activated microbubbles in close proximity to cells. Here, the selection of ultrasound settings according to the intended effect on the biological tissue remains a challenge, especially for broadly size-distributed microbubbles, which show a heterogeneous response to ultrasound. For this purpose, we have analyzed the general response of narrower size-distributed poly(

Indexed as

Biocompatible MaterialsEnbucrilateMicrobubblesMaterials TestingParticle SizeSonicationSurface PropertiesUltrasonic WavesBiocompatible MaterialsEnbucrilatecompression-only behaviorhard-shelled microbubblessonopermeationsonoporationTEER

Identifiers

PMID39900350
PMCPMC11836932

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.