SynthesisPloS one2025
Clinical efficacy of different methods for treatment of granulomatous lobular mastitis: A systematic review and network meta-analysis.
Synthesis in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Therapeutic strategies for idiopathic granulomatous mastitis: an umbrella review of systematic reviews and meta-analyses.Frontiers in medicine · 2026Pooled it
- Efficacy and safety of adalimumab as first-line therapy for treatment-naïve granulomatous lobular mastitis: an exploratory real-world study with propensity score-matching analysis.Clinical rheumatology · 2026Article
- Utility of intercostal artery perforator flap in granulomatous lobular mastitis: a single-center retrospective study.Gland surgery · 2026Article
- Article
- Granulomatous Mastitis Mimicking Infection: A Case Report of Therapeutic Challenges and Evolving Management.Cureus · 2026Article
- Molecular Targeted Therapy for Chronic Non-Bacterial Mastitis: New Insights into Pathophysiology and Therapeutic Strategies.International journal of women's health · 2026Review
- Local Triamcinolone Injection versus Anti-Tuberculosis Triple Therapy for Non-Puerperal Mastitis: A Comparative Study.International journal of women's health · 2026Article
- The paradoxical effect of oral prednisone in granulomatous lobular mastitis: An observational cohort study.PloS one · 2026Observational
- Commentary: Acupoint glucocorticoid injection combined with focused ultrasound for granulomatous lobular mastitis: a retrospective study.Frontiers in surgery · 2026Article
- Tuoli Tounong decoction promotes lesion resolution in granulomatous lobular mastitis by remodeling a Caspase-8-associated PANoptosis-like cell death network.Frontiers in immunology · 2026Article
- Article
- Evaluating the efficacy of topical steroids in idiopathic granulomatous mastitis: a prospective cohort study.Gland surgery · 2025Article
- Article
- Granulomatous lobular mastitis in pregnancy: report of 29 cases.Frontiers in oncology · 2025Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis network meta-analysis aims to evaluate the recurrence rates of various treatment options for granulomatous lobular mastitis.
methodsWe systematically searched and identified eligible studies in PubMed, EMBASE, Cochrane Library, and Web of Science databases until September 30, 2023. Original studies reporting the recurrence rates of various treatments were included. Subsequently, literature screening, data extraction, and network meta-analysis were conducted. This study was registered with PROSPERO (registration number CRD 42023434773).
resultsNineteen articles involving 1,095 patients were included in this study. The network meta-analysis revealed that several treatment combinations reduced the recurrence rate compared to observation: Surgery + Local steroid injection + Systemic steroids therapy (OR: 0.23, 95% CI 0.01 to 4.53), Local steroid injection (OR: 0.34, 95% CI 0.02 to 6.81), Surgery + Systemic steroids therapy (OR: 0.36, 95% CI 0.02 to 5.29), Surgery + Traditional Chinese Medicine (OR: 0.33, 95% CI 0.01 to 9.11), Systemic steroids therapy + MTX (OR: 0.62, 95% CI 0.01 to 34.59), and Systemic steroids therapy + drainage (OR: 0.76, 95% CI 0.05 to 10.67). Among these, Surgery + Local steroid injection + Systemic steroids therapy demonstrated superior efficacy. The surface under cumulative ranking curve (SUCRA) values were highest for Surgery + Local steroid injection + Systemic steroids therapy (0.85), followed by Local steroid injection (0.78) and Surgery + Systemic steroids therapy (0.77).
conclusionsSteroid-based combination therapy may be the first choice for IGM patients, with a comprehensive strategy of local and systemic steroids combined with surgery having the best effect on IGM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.