Evidence map›Paper›PMID 39899271›Full record

SynthesisNursing open2025

Association Between Frailty and Mortality, Falls and Hospitalisation Among Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis.

Wan-Qiao He, Xiao-Ming Zhang, Yi-Zhen Zhang, Wei Gai, Xin-Juan Wu, Yan-Ling Tao

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Nursing open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wan-Qiao HeChengdu Integrated TCM & Western Medicine Hospital, Chengdu, Sichuan, China.
Xiao-Ming ZhangDepartment of Emergency, The People's Hospital of Baoan Shenzhen, Shenzhen, Guangdong, China.
Yi-Zhen ZhangDepartment of Nursing, Longgang Central Hospital of Shenzhen, Shenzhen, Guangdong, China.
Wei GaiShaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.ORCID https://orcid.org/0009-0003-3002-4142
Xin-Juan WuDepartment of Nursing, Chinese Academy of Medical Sciences-Peking Union Medical College, Peking Union Medical College Hospital (Dongdan Campus), Beijing, China.ORCID https://orcid.org/0000-0002-9024-7941
Yan-Ling TaoDepartment of Nursing, Longgang Central Hospital of Shenzhen, Shenzhen, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimFrailty is a risk factor for adverse events in older individuals; however, it has not been fully verified in patients undergoing dialysis. Our aim was to verify the association between frailty and adverse outcomes consisting of mortality, falls and hospitalisation among patients undergoing dialysis by a systematic review and meta-analysis.

designSystematic review and meta-analysis.

methodsMultiple internet databases, were searched from the establishment of each database to April 2022, including the PubMed, EMbase, Cochrane, CNKI, WanFang and China Science and Technology Journal (VIP) databases. Cohort studies exploring the association between frailty and adverse outcomes among patients undergoing dialysis were analysed. The Newcastle Ottawa Scale (NOS) was used to assess the risk of bias in the included studies. A random effects model was used to pool the effect size, and comprehensive analyses consisting of subgroup analysis, sensitivity analysis and publication bias were assessed.

resultsThe search initially identified 2744 studies from six databases. After the screening, 26 studies including 14,089 patients with dialysis aged 44.95-78.10 years were included in the final analysis, all of which were observational cohort studies. The pooled results showed that frailty was a powerful predictor of adverse outcomes (mortality, falls and hospitalisation) among the patients. Therefore, dialysis patients should be screened for early frailty and appropriate interventions should be implemented to improve adverse outcomes.

Indexed as

Accidental FallsFrailtyHospitalizationMortalityRenal DialysisAgedHumansRisk Factorsdialysisfallsfrailtyhospitalisationmortality

Identifiers

PMID39899271
PMCPMC11789586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.