Evidence map›Paper›PMID 39899257›Full record

ReviewPharmacological reports : PR2025

Off-label use of anlotinib in malignancies' treatment: efficacy and management of adverse reactions.

Guangli Wang, Yuling Wang, Changhao Jin, Xiaodan Sun

Abstract readReview
In one paragraph

Review in Pharmacological reports : PR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guangli WangObstetrics and Gynecology Department, Yanbian University Affiliated Hospital, Yanbian, 133000, China.
Yuling WangObstetrics and Gynecology Department, Yanbian University Affiliated Hospital, Yanbian, 133000, China.
Changhao JinObstetrics and Gynecology Department, Yanbian University Affiliated Hospital, Yanbian, 133000, China.
Xiaodan SunThe First Department of Gynecological Oncology, Jilin Provincial Cancer Hospital, Changchun, 130012, China. 15640584861@163.com.ORCID http://orcid.org/0000-0002-5119-383X

Funding

Jilin Province Science and Technology Development Program Project YDZJ202501ZYTS183the Project of Lung Cancer Targeted Therapy Research of Beijing CSCO No. Y-2021AST/qn-0013
6 · The paper itself

Abstract

Anlotinib is a novel small-molecule multi-target tyrosine kinase inhibitor (TKIs) independently developed in China, it possesses the functions of inhibiting tumor angiogenesis and suppressing tumor growth. Anlotinib has achieved notable therapeutic effects in approved indications for advanced non-small cell lung cancer, soft tissue sarcoma, small cell lung cancer, and medullary thyroid carcinoma. Additionally, with unanimous expert consensus, it has been used off-label in various other tumors, yielding favorable outcomes. This article reviews the efficacy and common adverse reactions, as well as their management, of off-label use of anlotinib in various malignant tumors.

Indexed as

Antineoplastic AgentsIndolesNeoplasmsOff-Label UseProtein Kinase InhibitorsQuinolinesAnimalsHumansanlotinibAntineoplastic AgentsIndolesProtein Kinase InhibitorsQuinolinesAnlotinibManagement of adverse reactionsOff-label drug useTumor

Identifiers

PMID39899257
PMCPMC11911265

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.