Evidence map›Paper›PMID 39899232›Full record

SynthesisInternational journal of hematology2025

Prognostic value of Glasgow prognostic score in hematological malignancies: a systematic review and meta-analysis.

Lijun Jiang, Wenting Jin

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in International journal of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lijun JiangDepartments of Hematology, The Affiliated Hospital of Jiaxing University, No. 1882 Zhonghuan South Road, Nanhu District, Jiaxing, 314000, Zhejiang, China.
Wenting JinDepartments of Hematology, The Affiliated Hospital of Jiaxing University, No. 1882 Zhonghuan South Road, Nanhu District, Jiaxing, 314000, Zhejiang, China. jlj30793@163.com.

Funding

the Jiaxing Key Discipline Fund 2023-FC-005the Medical and Health Research Project of Zhejiang Province 2024KY1676
6 · The paper itself

Abstract

objectiveThe Glasgow prognostic score (GPS) is used to predict the prognosis of several cancers. This first systematic review and meta-analysis evaluated the role of GPS in predicting overall survival (OS) and progression-free survival (PFS) in patients with hematological malignancies.

methodsEmbase, PubMed, CENTRAL, Scopus, and Google Scholar were screened for studies evaluating the prognostic role of GPS in hematological malignancies.

resultsTwelve studies were eligible. Meta-analysis showed that patients with GPS of ≥1 and ≥2 had worse OS than those with GPS of 0. We noted that both GPS scores of ≥1 and ≥2 were associated with significantly poor PFS in patients with hematological malignancies. Results remained robust on sensitivity analysis.

conclusionGPS can be used as a predictor of OS and PFS in patients with hematological malignancies. High GPS scores can lead to a twofold higher risk of poor OS and PFS.

Indexed as

Hematologic NeoplasmsHumansPrognosisProgression-Free SurvivalInflammationLeukemiaLymphomaMyelomaPrognosis

Identifiers

PMID39899232

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.