Evidence map›Paper›PMID 39899212›Full record

ArticleInfection2025

Successful cure of multiple large, inoperable liver abscesses by antibiotic therapy.

Sarah Niederreiter, Andreas Voelkerer, Christian Datz, Guenter Weiss

Abstract readCase Reports
In one paragraph

Article in Infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah NiederreiterDepartment of Internal Medicine II, Medical University of Innsbruck, Anichstr. 35, Innsbruck, A-6020, Austria.
Andreas VoelkererDepartment of Internal Medicine, District Hospital of Oberndorf, Salzburg, Austria.
Christian DatzDepartment of Internal Medicine, District Hospital of Oberndorf, Salzburg, Austria.
Guenter WeissDepartment of Internal Medicine II, Medical University of Innsbruck, Anichstr. 35, Innsbruck, A-6020, Austria. guenter.weiss@i-med.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePyogenic liver abscesses are challenging due to their diverse etiology and the risk of severe complications. In many cases, surgical interventions are initiated. However, these are only applicable in selected scenarios. We report the case of a 63-year-old woman with multiple large liver abscesses of up to 6.7 cm spread across both liver lobes, which could not be managed surgically. METHODS &

resultsStreptococcus intermedius was isolated in blood culture and PCR positivity for this pathogen was obtained in liver puncture specimen. Following a two-weeks course of intravenous therapy with cefuroxime, metronidazole and fosfomycin, the patients received a consecutive, combined oral antibiotic treatment with clindamycin and cephalexin for four months. This resulted in complete resolution of the abscesses, with no evidence of relapse at follow-up.

conclusionThis case illustrates the complex therapeutic challenges in the management of multiple, large hepatic abscesses, highlighting the potential of antibiotic therapy to cure even inoperable patients.

Indexed as

Anti-Bacterial AgentsLiver AbscessLiver Abscess, PyogenicStreptococcal InfectionsStreptococcus intermediusAdministration, IntravenousDrug Therapy, CombinationFemaleHumansMiddle AgedTreatment OutcomeAnti-Bacterial AgentsAntibiotic therapy multiple liver abscessesInoperable liver abscesses

Identifiers

PMID39899212
PMCPMC12460355

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.