ReviewDiscover oncology2025
Relationship between programmed cell death and targeted therapy for thyroid cancer in patients with a poor prognosis: an update.
Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Improving predicted risk of recurrence using molecular profiling in papillary thyroid cancer.Scientific reports · 2026Article
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Authors and funding
5 authors.
Funding
Abstract
In recent years, the incidence of thyroid cancer has steadily increased. However, the detailed mechanisms of pathogenesis are still unclear. Therefore, a comprehensive understanding of the underlying carcinogenesis mechanisms of thyroid cancer is required. Programmed cell death (PCD) is a cell death process mediated by specific molecular program, regulated by specific genes within the cell. Accumulating evidence suggests that PCD plays an indispensable role in thyroid cancer, maintaining intracellular stability by regulating genes and eliminating damaged or aged cells. In this review, we summarize six identified forms of PCD, analyze biomarkers for different PCD pathways in thyroid cancer, and briefly elucidate the roles of various PCD pathways in targeted therapies for thyroid cancers with a poor prognosis. We also provide an outlook on future treatments for drug-resistant thyroid cancer, poorly differentiated thyroid cancer, and iodine-refractory thyroid cancer, aiming to accurately identify targets and offer effective targeted therapeutic strategies.
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