Evidence map›Paper›PMID 39899056›Full record

ArticleInternational journal of legal medicine2025

Socio-demographic and toxicological findings from autoptic cases in a Northern Italy community (2017-2022).

Federica Palazzoli, Tommaso Filippini, Antonino Lavenia, Simone Balduini, Alessia Attanasi, Patrizia Verri, Daniele Vandelli, Valentina Castagnetti, Anna Laura Santunione, Marco Vinceti and 1 more

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Article in International journal of legal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Federica PalazzoliInstitute of Legal Medicine, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy. federica.palazzoli@unimore.it.ORCID https://orcid.org/0000-0003-3954-9263
Tommaso FilippiniCREAGEN - Environmental, Genetic and Nutritional Epidemiology Research Center, Section of Public Health, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Antonino LaveniaInstitute of Legal Medicine, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Simone BalduiniInstitute of Legal Medicine, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Alessia AttanasiInstitute of Legal Medicine, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Patrizia VerriInstitute of Legal Medicine, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Daniele VandelliInstitute of Legal Medicine, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Valentina CastagnettiInstitute of Legal Medicine, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Anna Laura SantunioneInstitute of Legal Medicine, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Marco VincetiCREAGEN - Environmental, Genetic and Nutritional Epidemiology Research Center, Section of Public Health, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Rossana CecchiInstitute of Legal Medicine, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe overall trend in the use of licit and illicit substances is increasing. However, a few data on socio-demographic and toxicological findings in post-mortem cases are available.

methodsA retrospective study was conducted on autoptic cases evaluated in the Institute of Legal Medicine of the cities of Modena and Reggio Emilia in the period 2017-2022. Positivity to toxicological compounds and their relation with sociodemographic and forensic features were evaluated.

resultsA toxicological analysis was conducted in 504 cases out of 794 autopsies, finding 330 positive cases. An association was observed between positivity and increasing age, as well as manner of death. The most frequently observed classes of substances were benzodiazepine (41.2%), followed by alcohol (35.5%) and abuse drugs (24.8%). For every class of substances in at least half of the cases two or more classes were detected. As regards prescribed drugs, approximately 40% of cases assumed 2 or more drugs, while polypharmacy occurred in 6.1%.

conclusionsOlder age and specific causes of deaths appear to be associated with toxicological findings. In addition, co-assumption of licit and illicit substances emerged as a widespread phenomenon in our study population. Under a public health perspective, these data provide findings of relevance for preventive and therapeutic measures.

Indexed as

Substance-Related DisordersAdolescentAdultAgedAged, 80 and overAge DistributionCause of DeathChildFemaleForensic ToxicologyHumansIllicit DrugsItalyMaleMiddle AgedPolypharmacyIllicit DrugsBenzodiazepinesDrug abuseForensic toxicologyIllicit drugLicit drugPost-mortem

Identifiers

PMID39899056
PMCPMC12003492

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.