Evidence map›Paper›PMID 39898971›Full record

ReviewComprehensive reviews in food science and food safety2025

Phage-derived proteins: Advancing food safety through biocontrol and detection of foodborne pathogens.

Dahee Choi, Sangryeol Ryu, Minsuk Kong

Abstract readReview
In one paragraph

Review in Comprehensive reviews in food science and food safety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Isolation and Characterization of aJournal of microbiology and biotechnology · 2025
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dahee ChoiDepartment of Food Science and Biotechnology, Institute of Food and Biotechnology, Seoul National University of Science and Technology, Seoul, South Korea.ORCID 0009-0001-2662-1580
Sangryeol RyuDepartment of Food and Animal Biotechnology, Department of Agricultural Biotechnology, Seoul National University, Seoul, South Korea.
Minsuk KongDepartment of Food Science and Biotechnology, Institute of Food and Biotechnology, Seoul National University of Science and Technology, Seoul, South Korea.ORCID 0000-0002-6876-4520

Funding

Korea Health Industry Development Institute RS-2023-KH136866Ministry of Food and Drug Safety RS-2024-00332071
6 · The paper itself

Abstract

The emergence of antimicrobial-resistant foodborne pathogens poses a continuous health risk and economic burden as they can easily spread through contaminated food. Therefore, the demand for new antimicrobial agents to address this problem is steadily increasing. Similarly, the development of rapid, sensitive, and accurate pathogen detection tools is a prerequisite for ensuring food safety. Phage-derived proteins have become innovative tools for combating these pathogens because of their potent antimicrobial activity and host specificity. Phage proteins are relatively free from regulation compared to phages per se, and there are no concerns about the transduction of harmful genes. With recent progress in next-generation sequencing technology, the analysis of phage genomes has become more accessible, and numerous phage proteins with potential for biocontrol and detection have been identified. This review provides a comprehensive overview of phage protein research on food safety from 2006 to the present, a pivotal period marked by the certification of phages as Generally Recognized As Safe (GRAS). Emphasizing recent advancements, we investigated the diverse applications of various phage proteins for biocontrol and detection purposes. While highlighting the successful implementation of these proteins, we also address the current bottlenecks and propose strategies to overcome these challenges. By summarizing the current state of research on phage-derived proteins, this review contributes to a deeper understanding of their potential as effective antimicrobial agents and tools for detecting foodborne pathogens.

Indexed as

BacteriophagesFood SafetyViral ProteinsBacteriaBiological Control AgentsFoodborne DiseasesFood MicrobiologyHumansBiological Control AgentsViral Proteinsbacteriophage tail proteinsbiocontroldetectionendolysinfoodborne pathogens

Identifiers

PMID39898971
PMCPMC11891642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.