ArticleKorean journal of radiology2025
Radiofrequency Ablation of Benign Thyroid Nodules: 10-Year Follow-Up Results From a Single Center.
Article in Korean journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Feasibility, safety, and short-term efficacy of ultrasound-guided radiofrequency ablation for abdominal wall endometriosis: preliminary results from a single center.Abdominal radiology (New York) · 2026Article
- New gadgets for thyroid ablation-what's the promise?Gland surgery · 2026Article
- Mid-to Long-term Outcomes After Single Radiofrequency Ablation of Nontoxic and Toxic Thyroid Nodules.The Journal of clinical endocrinology and metabolism · 2026Article
- Predictors of retreatment after radiofrequency ablation of benign thyroid nodules: role of pre-treatment growth rate and viable volume.European thyroid journal · 2026Article
- Novel approach of thyroid radiofrequency ablation for huge nodules-Eggshell technique (evenly margin-preserving ablation): a case report.Gland surgery · 2025Article
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Authors and funding
4 authors.
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Abstract
objectiveThe long-term efficacy of radiofrequency ablation (RFA) for the treatment of benign thyroid nodules remains unclear. We aimed to evaluate the long-term efficacy, emphasizing single-session RFA, and identify the factors associated with cases requiring additional RFA sessions to achieve a comparable volume reduction rates (VRR). MATERIALS AND
methodsWe retrospectively evaluated benign thyroid nodules treated with RFA between 2008 and 2018. Treatment efficacy at the 5- and 10-year follow-ups was analyzed. Additionally, subgroup analysis comparing technique efficacy, such as the final VRR, between the single- and multi-session RFA groups was performed. Continuous variables were analyzed using the two-sample t-test or Mann-Whitney U test, and categorical variables were analyzed using the Chi-square or Fisher's exact test.
resultsA total of 267 nodules from 237 patients (age: 46.3 ± 15.0 years; female: 210/237 [88.6%]) were included. Of these, 60 were analyzed for the 5-year follow-up (mean follow-up duration ± standard deviation: 5.8 ± 0.4 years) and 29 for the 10-year follow-up (10.9 ± 0.9 years). Single-session RFA showed a median VRR of 95.7% (5th year) and 98.8% (10th year), while multi-session RFA showed comparable median VRRs of 97.4% (5th year) and 96.9% (10th year). The vascularity type, demographic factors, nodular components, and locations did not significantly differ between the single-session and multi-session RFA groups. However, nodules with pre-RFA volume <10 mL were more prevalent in the single-session RFA group than in the multi-session RFA group (5th year: 64.3% [18/28] vs. 34.4% [11/32],
conclusionSingle-session RFA may be sufficient for achieving adequate volume reduction during long-term follow-up for small-volume benign thyroid nodules. A high VRR was maintained regardless of the nodular component, location, demographic factors, or vascularity type. However, large-volume nodules may require multiple RFA sessions to achieve a comparable VRR.
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