Evidence map›Paper›PMID 39898366›Full record

ArticleJournal of exercise science and fitness2025

Comparison of trabecular bone microarchitecture between older males with and without a running habit: A cross-sectional study.

Chuan Zhang, Shubo Wang, Fanjing Meng, Dingbo Shu, Haizhen Huang, Yanjing Zhang, Siyu Dai

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Article in Journal of exercise science and fitness, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chuan ZhangSchool of Physical Education and Sport, Central China Normal University, Wuhan, China.
Shubo WangGlobus Medical Inc., Audubon, PA, USA.
Fanjing MengSchool of Clinical Medicine, Hangzhou Normal University, Hangzhou, China.
Dingbo ShuZhejiang University Shaoxing Hospital, Shaoxing, China.
Haizhen HuangSchool of Physical Education and Sport, Central China Normal University, Wuhan, China.
Yanjing ZhangThe Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Siyu DaiSchool of Clinical Medicine, Hangzhou Normal University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Despite its prevalence among seniors, the impact of running on trabecular bone microarchitecture, especially in weight-bearing sites, remains relatively unexplored. This cross-sectional study aimed to investigate the impact of habitual running on bone health, specifically bone mineral density (BMD) and trabecular bone microarchitecture, in male older adults. Methods: Twenty-five male recreational runners aged between 50 and 75 years old were recruited in this study (RUN; average running experience 7.5 ± 6.0 years, average monthly running volume 217 ± 120 km), and 25 age matched sedentary older males served as controls (CON). Dual-energy X-ray absorptiometry was used to obtain bone mineral density (BMD) measures at whole-body, bilateral proximal femur as well as lumbar spine for all participants. Magnetic resonance imaging was used to obtain trabecular bone microarchitectural parameters at distal femur and distal tibia for all participants. Results: Findings revealed no significant difference in BMD between groups for all measured sites (all p > 0.05; d range 0.013-0.540). However, runners displayed higher bone volume fraction and trabecular thickness at the distal tibia (p = 0.012 and 0.001; 95 % CI of MD [-0.030, -0.004] and [-0.013, -0.004]; d = 0.739 and 1.034, respectively) and higher trabecular thickness at the distal femur (p = 0.002; 95 % CI of MD [-0.010, -0.002]; d = 0.907). Conclusions: This study provides critical insights into the relationship between running and bone health in older adults, suggesting regular recreational running may positively influence trabecular bone microarchitecture, potentially enhancing bone strength and reducing fracture risk. These findings pave the way for future research to develop evidence-based exercise recommendations for an aging population.

Indexed as

Dual-energy X-ray absorptiometryMagnetic resonance imagingMechanical loadingRunningTrabecular bone morphology

Identifiers

PMID39898366
PMCPMC11786814

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.