ArticlePain reports2025
Ultrasound-guided rhomboid intercostal block combined with subserratus plane block vs pectoral nerve block type-2 in analgesia for breast-conserving surgery (randomized, controlled study).
Article in Pain reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- The Comparison of Efficacy of Bilateral Type I Versus Type II Pectoral Nerve Block Applied with Ultrasound-Guided for Postoperative Analgesia in Gynecomastia Surgeries.Aesthetic plastic surgery · 2025Trial
- Comparison of analgesic efficacy of erector spinae plane block with rhomboid intercostal subserratus plane block in patients undergoing modified radical mastectomy: A randomised control trial.Indian journal of anaesthesia · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The most frequent malignancy in women is the breast cancer, the rhomboid intercostal and subserratus plane (RISS) block is a novel regional approach. Objectives: This study evaluated the analgesic efficacy of the RISS block compared to type 2 Pectoral Nerve (PECS II) block in breast cancer patients following breast-conserving surgery (BCS). Methods: This randomized controlled trial comprised 69 women with breast cancer scheduled for unilateral BCS under general anesthesia, randomly allocated into 3 equal groups. The RISS group had unilateral RISS block using 20 mL of 0.25% bupivacaine between rhomboid major and intercostal muscles and an equal volume between external intercostal and serratus anterior muscles. The PECs Group received a PECS II block using 20 mL of 0.25% bupivacaine between pectoralis major and minor muscles and 10 mL between pectoralis major and serratus muscles. The control group did not get any blocks. The primary outcome was total postoperative morphine consumption within 24 hours. The secondary outcomes were pain score, first request for rescue analgesia, intraoperative fentanyl consumption, and hemodynamics. Results: Requesting rescue morphine analgesia was significantly less frequent in the RISS and PECs groups compared to controls (5, 1, and 23 patients, respectively, Conclusion: In patients undergoing BCS, RISS and PECs II block are comparable, safe, and effective regional analgesic alternatives.
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