Evidence map›Paper›PMID 39898123›Full record

ReviewFood science & nutrition2025

Structure, Properties, and Biomedical Activity of Natural Sweeteners Steviosides: An Update.

Aoyi Wang, Huiqin Hu, Yadan Yuan, Shiran Mei, Guoxue Zhu, Qiaoyan Yue, Yanliang Zhang, Shujun Jiang

Abstract readReview
In one paragraph

Review in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. AI/ML-based computational models for toxicity prediction.Environmental science and pollution research international · 2026
    Review
  2. Steviol Glycosides (E960) FromFood science & nutrition · 2026
    Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aoyi WangNanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine Nanjing China.
Huiqin HuNanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine Nanjing China.
Yadan YuanNanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine Nanjing China.
Shiran MeiNanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine Nanjing China.
Guoxue ZhuNanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine Nanjing China.
Qiaoyan YueNanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine Nanjing China.
Yanliang ZhangNanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine Nanjing China.
Shujun JiangNanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine Nanjing China.ORCID https://orcid.org/0000-0001-7995-4330

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stevioside is a natural sweetener with the characteristics of low calorie and high sweetness. It comprises a diverse range of monomers that play crucial roles in numerous biological processes. Due to these attributes, it has gained widespread application in agriculture, food, and pharmaceutical industries. As a substitute for sugar, stevioside also shows good pharmacological activities on glucose metabolism, bodyweight keeping, blood pressure maintenance, and shows anti-inflammatory, anti-oxidation, anti-tumor, antibacterial, and immune regulation activities. This review summarized the update on the food safety, sweet structure-activity relationship, pharmacological activity of stevia glycosides recently, and discussed the limitations of its application in food and medicine.

Indexed as

biomedical activitysafetystevioside

Identifiers

PMID39898123
PMCPMC11787980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.