Evidence map›Paper›PMID 39898039›Full record

ArticleiScience2025

Interferon-gamma rescues dendritic cell calcineurin-dependent responses to

Amit Adlakha, Thomas J Williams, Xinxin Shou, Anna K Reed, Boris Lenhard, Darius Armstrong-James

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Pathogenesis and Triazole Resistance inInfection and drug resistance · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amit AdlakhaDepartment of Infectious Disease, Faculty of Medicine, Imperial College, London SW7 2AZ, UK.
Thomas J WilliamsDepartment of Infectious Disease, Faculty of Medicine, Imperial College, London SW7 2AZ, UK.
Xinxin ShouDepartment of Infectious Disease, Faculty of Medicine, Imperial College, London SW7 2AZ, UK.
Anna K ReedDepartment of Cardiothoracic Transplantation and Mechanical Support, Harefield Hospital, Royal Brompton & Harefield Hospitals, Part of Guy's and St. Thomas' NHS Foundation Trust & Imperial College, London UB9 6JH, UK.
Boris LenhardMRC London Institute of Medical Sciences, Imperial College, London W12 0NN, UK.
Darius Armstrong-JamesDepartment of Infectious Disease, Faculty of Medicine, Imperial College, London SW7 2AZ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive pulmonary aspergillosis is a lethal opportunistic fungal infection in transplant recipients receiving calcineurin inhibitors. We previously identified a role for the calcineurin pathway in innate immune responses to

Indexed as

MicrobiologyPathophysiologyTranscriptomics

Identifiers

PMID39898039
PMCPMC11787545

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.