ArticleiScience2025
National antibiotic consumption is strongly related to the prevalence of antibiotic resistance across bacterial clades.
Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Comparative pangenome analysis of Yersinia enterocolitica in a one health approach.BMC genomics · 2025Article
- Health and Psychological Predictors of Antibiotic Use in Infancy and Fathers' Role.European journal of investigation in health, psychology and education · 2025Article
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Authors and funding
1 author.
Funding
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Abstract
The impact of societal antibiotic consumption on the prevalence of antibiotic resistance across microbial taxa in natural environments has not yet been assessed at global scales. Here, I examine the prevalence of 155 antibiotic resistance genes (ARGs) in 300,209 bacterial genomes, from non-clinical non-human-associated terrestrial environments at over 9,600 locations in 44 countries. I then compare ARG prevalences to nationwide antibiotic consumption rates, distinguishing between different ARG types. I find that depending on country and ARG type, ARG prevalences can be extremely high; for example, the probability that a given quinolone resistance gene is present in a given strain in Thailand was estimated at 42%. Further, I find strong positive correlations between nationwide antibiotic consumption rates and mean ARG prevalences for nearly all ARG types. Thus, national antibiotic consumption leaves a signal on the prevalence of ARGs across the bacterial tree, even in non-clinical environments.
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