ArticleJAAD international2025
Atopic dermatitis in childhood and pubertal development: A nationwide cohort study.
Article in JAAD international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Atopic dermatitis and fecundity: a Danish National Birth Cohort study.Human reproduction open · 2026Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Atopic dermatitis (AD) might delay puberty, but research is lacking. Objective: To investigate the association between AD and puberty. Methods: A subcohort within the Danish National Birth Cohort includes children born between 2000 and 2003, with mothers reporting doctor-diagnosed AD at 6 months, 18 months, and 7 years old. The National Patient Registry identified hospital-diagnosed AD. From 11 years, the children give half-yearly information on pubertal development. We estimated the mean age difference in months at attaining Tanner stages 1 to 5 and the development of axillary hair, acne, first ejaculation, voice break, and age at menarche, using an interval-censored regression model. Results: In total, 15,534 children participated, 21.5% had self-reported doctor-diagnosed AD and 0.7% had hospital-diagnosed AD. For girls with self-reported doctor-diagnosed AD, the average age difference at reaching all pubertal milestones was 0.0 months (95% confidence interval [CI]: -0.8; 0.8), and for hospital-diagnosed AD, it was -0.3 months (95% CI: -5.4; 4.8). For boys, the average age difference was 0.1 months (95% CI: -0.6; 0.9) and -0.3 months (95% CI: -3.6; 3.0), respectively. Limitations: No information on treatment was available. Missing data on covariates (<5%) were not addressed. Conclusion: No association was found between AD and puberty in either girls or boys.
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