Evidence map›Paper›PMID 39898008›Full record

ArticleNeurobiology of stress2025

Shared genetic risk and causal associations between Post-traumatic stress disorder and migraine with antithrombotic agents and other medications.

Charlotte K Bainomugisa, International Headache Genetics Consortium (IHGC), Dagmar Bruenig, Heidi G Sutherland, Lyn R Griffiths, Dale R Nyholt, Divya Mehta

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurobiology of stress, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Charlotte K BainomugisaCentre for Genomics and Personalised Health, Queensland University of Technology, Brisbane, Queensland, Australia.
International Headache Genetics Consortium (IHGC)
Dagmar BruenigCentre for Genomics and Personalised Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Heidi G SutherlandCentre for Genomics and Personalised Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Lyn R GriffithsCentre for Genomics and Personalised Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Dale R NyholtCentre for Genomics and Personalised Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Divya MehtaCentre for Genomics and Personalised Health, Queensland University of Technology, Brisbane, Queensland, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-traumatic stress disorder (PTSD) is a psychiatric disorder that frequently co-occurs with pain disorders including migraine. There are proposed biological, genetic and environmental factors associated with both PTSD and migraine suggesting shared etiology. Genome-Wide Association Studies (GWAS) have been used to identify genomic risk loci associated with various disorders and to investigate genetic overlap between traits. There is a significant genetic correlation between PTSD and migraine with no evidence of a causal relationship that could be attributed to pleiotropy. Cross-disorder genetic analyses were applied to investigate the genetic overlap and causal associations using GWAS summary statistics of PTSD (

Indexed as

GenesGWASLociMedicationMigrainePTSD

Identifiers

PMID39898008
PMCPMC11786899

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.