Effects of collagen and chondroitin sulfate on relaxation at multiple magnetic field strengths.

Olli-Pekka Aro, Victor Casula, Nina E Hänninen, Jouni Karjalainen, Mikko J Nissi, Miika T Nieminen, Henning Henschel

Abstract read

In one paragraph

Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Olli-Pekka AroResearch Unit of Health Sciences and Technology, University of Oulu, Oulu, Finland.

Victor CasulaResearch Unit of Health Sciences and Technology, University of Oulu, Oulu, Finland.

Nina E HänninenResearch Unit of Health Sciences and Technology, University of Oulu, Oulu, Finland.

Jouni KarjalainenResearch Unit of Health Sciences and Technology, University of Oulu, Oulu, Finland.

Mikko J NissiResearch Unit of Health Sciences and Technology, University of Oulu, Oulu, Finland.

Miika T NieminenResearch Unit of Health Sciences and Technology, University of Oulu, Oulu, Finland.

Henning HenschelResearch Unit of Health Sciences and Technology, University of Oulu, Oulu, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To elucidate the connection between MRI relaxation properties of articular cartilage and tissue composition, in terms of collagen and chondroitin sulfate (CS). Additional aims were to determine the effect of different magnetic field strengths, as well as the effect of concentrations of the components on relaxation properties. Methods: A series of MRI phantoms consisting of gels containing collagen and chondroitin sulfate were prepared with final concentrations of collagen in the range 20-60 mg/g and the CS concentration in the range 0-40 mg/g. Results: Relaxation rates generally increased with increasing concentration of either of the compounds. Conclusions: Our results suggest that

Indexed as

CartilageChondroitin sulfateCollagenGel phantomRelaxivity

Identifiers

PMID39897856

DOI10.1016/j.heliyon.2025.e41854

PMCPMC11783438

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.