Mycophenolate-associated colitis in an orthotopic heart transplant patient- an unusual case presentation.

Hajra Arshad, Mohammad Yasrab, Alejandra Blanco, Jacqueline E Birkness-Gartman, Elliot K Fishman

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Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Hajra ArshadThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA.

Mohammad YasrabThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA.

Alejandra BlancoThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA.

Jacqueline E Birkness-GartmanDepartment of Pathology, Division of Gastrointestinal/Liver Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Elliot K FishmanThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA.

Funding

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6 · The paper itself

Abstract

Mycophenolate mofetil (MMF), an immunosuppressive, is a pharmacologically inactive compound of mycophenolic acid, which has been widely used in solid organ transplant and autoimmune conditions. It mostly exerts gastrointestinal (GI) adverse effects, which include diarrhea, abdominal pain, nausea, and vomiting. It can lead to MMF-colitis, a challenging condition to diagnose due to its similarity with other GI-related conditions and infections. This case report discusses a heart transplant recipient who developed severe MMF-induced colitis. It adds significantly to the limited literature available for this difficult-to-diagnose condition. It also highlights the severity of the condition and underscores the importance of vigilant monitoring and the need for future cohort studies to set guidelines for diagnosing and treating MMF-associated colitis due to its widespread use.

Indexed as

Drug-associated colitisGastrointestinal complicationsImmunosuppressionMycophenolate-associated colitisOrthotopic heart transplant

Identifiers

PMID39897747

DOI10.1016/j.radcr.2024.12.041

PMCPMC11783210

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LicenceCC BY-NC-ND

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