Evidence map›Paper›PMID 39897591›Full record

ReviewFrontiers in medicine2025

MHC class II of different non-professional antigen-presenting cells mediate multiple effects of crosstalk with CD4

Ming-Yan Wang, Yu Qiao, Shan-Jie Wei, Zhao-Liang Su, Hong-Yan Lu

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
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  5. Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ming-Yan WangDepartment of Pediatrics, The Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Yu QiaoDepartment of Pediatrics, The Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Shan-Jie WeiDepartment of Pediatrics, The Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Zhao-Liang SuInternational Genome Center, Jiangsu University, Zhenjiang, China.
Hong-Yan LuDepartment of Pediatrics, The Affiliated Hospital of Jiangsu University, Zhenjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The respiratory system is continuously exposed to the outside world, making it vulnerable to airborne particles and harmful pathogens like bacteria and viruses that can enter through breathing. Antigen presenting cells (APCs) have a vital function in the innate immune response as they present antigens to T cells and initiate the response of adaptive immune cells. Professional APCs engulf foreign microorganisms and display their peptides to T lymphocytes using MHC molecules. MHC II on their cell surface and potentially present antigen to CD4

Indexed as

alveolar epithelial cellsantigen-presenting cellslung diseasemajor histocompatibility complexT cells

Identifiers

PMID39897591
PMCPMC11782049

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.