Evidence map›Paper›PMID 39897585›Full record

ArticleBioactive materials2025

Dynamic hierarchical ligand anisotropy for competing macrophage regulation

Kanghyeon Kim, Sunhong Min, Ramar Thangam, Kyong-Ryol Tag, Hyun-Jeong Lee, Jeongyun Heo, Hwapyung Jung, Thet Thet Swe, Iman Zare, Guosheng Song and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Kanghyeon KimDepartment of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.
Sunhong MinDepartment of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.
Ramar ThangamDepartment of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.
Kyong-Ryol TagDepartment of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.
Hyun-Jeong LeeDepartment of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.
Jeongyun HeoCenter for Theragnosis, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Hwapyung JungDepartment of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.
Thet Thet SweDepartment of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.
Iman ZareResearch and Development Department, Sina Medical Biochemistry Technologies Co., Ltd., Shiraz, 7178795844, Iran.
Guosheng SongState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China.
Alireza Hassani NajafabadiTerasaki Institute for Biomedical Innovation, Los Angeles, CA, 90064, USA.
Junmin LeeDepartment of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH), Pohang, 790-784, Republic of Korea.
Hyun-Do JungDivision of Materials Science and Engineering, Hanyang University, Seoul, 04763, Republic of Korea.
Jong Seung KimDepartment of Chemistry, Korea University, Seoul, 02841, Republic of Korea.
Sunghoon HurElectronic Materials Research Center, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Hyun-Cheol SongElectronic Materials Research Center, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Sung-Gyu ParkDepartment of Nano-Bio Convergence, Korea Institute of Materials Science (KIMS), Changwon, Gyeongnam, 51508, Republic of Korea.
Kunyu ZhangSchool of Biomedical Sciences and Engineering, Guangzhou International Campus, South China University of Technology, Guangzhou, 511442, China.
Pengchao ZhaoSchool of Biomedical Sciences and Engineering, Guangzhou International Campus, South China University of Technology, Guangzhou, 511442, China.
Liming BianSchool of Biomedical Sciences and Engineering, Guangzhou International Campus, South China University of Technology, Guangzhou, 511442, China.
Se Hoon KimCenter for Theragnosis, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Juyoung YoonDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea.
Jae-Pyoung AhnAdvanced Analysis Center, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Hong-Kyu KimAdvanced Analysis Center, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Heemin KangDepartment of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diverse connective tissues exhibit hierarchical anisotropic structures that intricately regulate homeostasis and tissue functions for dynamic immune response modulation. In this study, remotely manipulable hierarchical nanostructures are tailored to exhibit multi-scale ligand anisotropy. Hierarchical nanostructure construction involves coupling liganded nanoscale isotropic/anisotropic Au (comparable to few integrin molecules-scale) to the surface of microscale isotropic/anisotropic magnetic Fe

Indexed as

Hierarchical ligand nanostructureMulti-scale ligand anisotropyRemote manipulationReversible macrophage regulation

Identifiers

PMID39897585
PMCPMC11787691

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.